末端酶及其在噬菌体包装中的作用

摘要/Abstract

摘要： 噬菌体的末端酶是一类寡聚体多功能蛋白，由大小亚基组成，在噬菌体DNA包装过程中有重要作用。大亚基是多功能酶，在包装中起主要作用；小亚基与基因组特异性结合，引导包装进程的进行。综述末端酶定位、结构和功能以及在噬菌体包装过程中的作用。

关键词: 噬菌体, 末端酶, 包装, 寡聚蛋白

Abstract: Terminase of bacteriophage which contains small subunit and large subunit is a family of multifunctional oligomeric protein. It’s important for the packaging. Large subunit is a multifunctional enzyme and plays a major role in the packaging. Small subunit specific binds the genomic DNA of bateriophage and guides the process of packaging. This paper reviews the position of the terminase, structure, function and the role in packaging process.

Key words: Bacteriophage, Terminase, Packaging, Oligomeric protein

宋少云, 贾艳华, 祝心舟, 庞义. 末端酶及其在噬菌体包装中的作用[J]. 生物技术通报, 2013, 0(11): 40-45.

Song Shaoyun, Jia Yanhua, Zhu Xinzhou, Pang Yi. Terminase and Its Function in Packaging Process of Bacteriophage[J]. Biotechnology Bulletin, 2013, 0(11): 40-45.

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