环境雌激素对生殖腺及卵黄蛋白原影响的研究进展

摘要/Abstract

摘要： 环境雌激素(EEs) 是能够干扰人与动物体正常内分泌活动, 进而影响生殖功能的一类化合物。归纳总结EEs对动物生殖腺结构、性别比例及卵黄蛋白原合成等影响的研究成果。建议将雄性或幼体卵生脊椎动物体内非正常表达的卵黄蛋白原水平作为监测环境中EEs时的指标;EEs对人与动物生殖功能影响的机制研究, 应考虑从单种EEs对模式动物入手。

关键词: 环境雌激素, 卵黄蛋白原, 生殖腺

Abstract: Environmental estrogens(EEs)is able to disturb normal endocrine activity of human and animal, the affect reproductive functions. This paper summarized the recent researches on the effect of EEs on animal reproductive gland structure, sex ratio and vitellogenin synthesis. We recommend to determine the vitellogenin levels of abnormal expression in male or larvae of oviparous vertebrates as EEs index in environmental monitoring;mechanism research on the influence of EEs on reproductive function of human and animal, should be start from a single compound in EEs.

Key words: Environmental estrogens, Vitellogenin, Gonad

贾毅娜, 梁刚. 环境雌激素对生殖腺及卵黄蛋白原影响的研究进展[J]. 生物技术通报, 2013, 0(6): 46-52.

Jia Yina, Liang Gang. Research Progression of Animal Gonad and Vitellogenin Under the Influence of Environmental Estrogens[J]. Biotechnology Bulletin, 2013, 0(6): 46-52.

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