The Research Progress of EPSP Synthase

Abstract

Abstract: 5-Enolpyruvylshikimate-3-phosphate synthase（EPSP synthase for short）, is the sixth enzyme of shikimic acid pathway and participates in the synthesis of aromatic amino acids and some of secondary metabolites. Meanwhile, EPSP synthase are not only targets of the herbicide（glyphosate）, antibiotics, anti-parasitic drugs, but also is important regulatory site of promoting the accumulation of shikimic acid in the organism. In recent years, with the rapid development of molecular biology technology and the in-depth study of EPSP synthase, EPSP synthase genes have been widely used in resistance to glyphosate genetically modified crops, medicine and health, etc. The research progress of EPSP synthase were reviewed and prospects in this paper.

Key words: Shikimate pathway, EPSP synthase, Shikimic acid accumulation, Resistance to glyphosate

Xu Jie, Jiang Shiyun, Fu Fengming, Geng Pengfei, Huang Kai. The Research Progress of EPSP Synthase[J]. Biotechnology Bulletin, 2014, 0(6): 40-50.

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