Applications of Liquid Chromatography-Mass Spectrometry in the Qualitative Analysis of Peptides and Proteins

Abstract

Abstract: With liquid chromatography-mass spectrometry（LC-MS）technology developing continuously, the system of LC-MS is widely used in pharmaceutical analysis, food analysis, environmental analysis and related fields. LC-MS provides powerful function of structure identification, which includes the ability of separation by LC and the advantages of high resolution, high sensitivity, high selectivity by MS. These advantages demonstrate that LC-MS will be applied in more related fields. In recent years, many researches were carried out in the identification of biological macromolecules by LC-MS. The analysis of peptide and protein qualitatively by LC-MS is reviewed.

Key words: Liquid chromatography-mass spectrometry（LC-MS）, Peptides and proteins, Qualitative analysis

Fan Xuehai, Zhu Yishen, Chen Lanting, Li Wenhui, Wei Ping. Applications of Liquid Chromatography-Mass Spectrometry in the Qualitative Analysis of Peptides and Proteins[J]. Biotechnology Bulletin, 2014, 0(6): 62-66.

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