Biotechnology Bulletin ›› 2014, Vol. 0 ›› Issue (10): 23-32.

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Thyroid Hormone Signaling Pathway and Its Research Advance in Marine Invertebrate

Xu Jianbo, Zhang Lili, Wang Yilei, Wang Guodong   

  1. Fisheries College,Jimei University,Key Laboratory of Healthy Mariculture for the East China Sea,Ministry of Agriculture,Institute of Aquaculture Biotechnology,Jimei University,Xiamen 361021
  • Received:2014-02-28 Online:2014-10-20 Published:2014-10-17

Abstract: In vertebrates, thyroid hormones(THs)signaling pathway is essential for the animal’s growth, development and energy metabolism. In addition, it also involved in metamorphosis process of the amphibian and fish. In recent, increasing evidence supports the existence of signal molecules of THs signaling pathway in marine invertebrates, such as endogenous THs and thyroid hormone receptors(TRs)and so on. And, these signal molecules involved in the development and metamorphosis process of marine invertebrates. It suggests that the THs signaling pathway exists in marine invertebrates, and it shows similarity with the vertebrates. This paper aims at a summary of thyroid hormone signaling pathway and its research advance in marine invertebrate, so as to provide basic data for the study of biological function of THs signaling pathway in marine invertebrates.

Key words: Marine invertebrates, Thyroid hormones, Thyroid peroxidase, Iodothyronine deiodinases, Thyroid hormone receptors