Biotechnology Bulletin ›› 2018, Vol. 34 ›› Issue (1): 15-25.doi: 10.13560/j.cnki.biotech.bull.1985.2017-0996

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The Research Progress of the Endoplasmic Reticulum(ER)Stress Response in Plant

CHEN Qian1,2, XIE Qi1,2   

  1. 1. State Key Laboratory of Plant Genomics,National Center for Plant Gene Research,Institute of Genetics and Developmental Biology,Chinese Academy of Sciences,Beijing 100101;
    2. University of Chinese Academy of Sciences,Beijing 100049
  • Received:2017-11-21 Online:2018-01-26 Published:2018-01-22

Abstract: Endoplasmic reticulum(ER)is a crucial site for the synthesis of membrane proteins and secretory proteins,as well as the preliminary modification of new peptides. Only the peptides that finished their preliminary modification like disulfide bonds formation,hydroxylation and glycosylation,they can enter the Golgi apparatus for further modification and eventually reach their correct protein conformation. However,the folding and modification process is complex and error-prone. If the cells face some endogenous or exogenous stresses,the probability of errors is greatly increased. The misfolded proteins were recognized and retained in ER by ER quality control system. The over-accumulated of the misfolded proteins in ER caused a series of response,which called ER stress response. They are mainly formed by UPR,ERAD,ERQC autophagy and cell death. These processes have been systematically studied in the field of yeasts and animals. This review mainly summarized the conserved mechanism in higher organism and the advances in the plant research. We hope to provide a reference for researchers who are concerned with the process of plant growth,development and plant stress response.

Key words: ER stress, UPR, ERAD, plant, stress