Abstract: Food-borne pathogenic microorganisms are the main biological hazards that contaminate food and edible-agricultural products and seriously threaten the health of humans and animals. At the same time,they also cause huge economic losses to food and edible-agricultural products industry,which is the key factor of restricting their development. Traditional dependence on antibiotics has a significant effect on pathogenic microorganism prevention and control. However,due to long-term unreasonable use or even abuse of antibiotics,the drug resistance of pathogenic microorganisms,as well as potential harmfulness to normal functions of internal organs,intestinal tissues,nervous and metabolic systems in humans and animals,are also prominent. Antimicrobial bioactive peptides,as biological peptides with antimicrobial functions,are considered as antimicrobial substances friendly to humans,animals and ecological environment,and they expected to replace antibiotics in pathogenic microorganism prevention and control. Now,antimicrobial bioactive peptide has become a hot spot to explore new and safe antibacterial drugs. In this paper,we comprehensively sort out their types,pollution characteristics and main hazard risks of food-borne pathogenic microorganisms,and systematically summarize their main types and source of antimicrobial bioactive peptides and their creation techniques. Then we emphatically introduce the current research status of antimicrobial bioactive peptides for food-borne pathogenic microorganism prevention and control. Finally,we discuss their application prospect,existing issues and countermeasures. To sum up,this paper is to provide the latest references or innovative idea for screening as well as prevention and control of food-borne pathogenic microorganisms in food and edible agricultural products.

Key words: food quality and safety, food-borne pathogenic microorganism, antimicrobialbioactive peptides, biologicalprevention and control