生物技术通报 ›› 2014, Vol. 0 ›› Issue (2): 30-40.
刘月星1,2, 马洪雨1, 马春艳1, 蒋伟1,2, 李淑娟1,2, 马凌波1
收稿日期:
2013-08-16
出版日期:
2014-02-27
发布日期:
2014-02-27
作者简介:
刘月星,男,硕士研究生,研究方向:水生生物学;E-mail:sjslyx@163.com
基金资助:
Liu Yuexing1,2, Ma Hongyu1, Ma Chunyan1, Jiang Wei1,2, Li Shujuan1,2, Ma Lingbo1,
Received:
2013-08-16
Published:
2014-02-27
Online:
2014-02-27
摘要: 随着基因组学技术的快速发展,已经在水产动物中鉴定出了大量的功能基因,并通过建立基因多态性与重要经济性状之间的关联,挖掘出了与经济性状连锁的优势等位基因和基因型。对基因资源的研究不仅有助于理解经济性状的分子调控机制,而且将为分子辅助育种提供理论指导和技术支持。综述了近年来水产动物重要经济性状相关基因的研究进展,以期为解析功能基因的分子调控机制和分子辅助育种提供基础理据和参考资料。
刘月星, 马洪雨, 马春艳, 蒋伟, 李淑娟, 马凌波. 水产动物重要经济性状相关功能基因的研究进展[J]. 生物技术通报, 2014, 0(2): 30-40.
Liu Yuexing, Ma Hongyu, Ma Chunyan, Jiang Wei, Li Shujuan, Ma Lingbo,. Research Progress of Functional Genes Related with Important Economic Traits for Aquatic Animals[J]. Biotechnology Bulletin, 2014, 0(2): 30-40.
[1] 宋九洲, 张沅. 分子遗传标记和数量性状位点(QTL)间的连锁分析[J]. 农业生物技术学报, 1994, 2(2):17-24. [2] Byrne P, Mcmullen M. Defining genes for agricultural traits:QTL analysis and the candidate gene approach[J]. Probe, 1996, 7(1):24-27. [3] Rothschild M, Soller M. Candidate gene analysis to detect genes controlling traits of economic importance in domestic livestock[J]. Probe, 1997, 8(1):13-20. [4] 王晓通, 王晓娜, 娄义洲. 候选基因法在动物育种中的应用[J]. 畜牧与饲料科学, 2004, 25(3):36-39. [5] 徐宁迎. 候选基因法检测家畜数量性状基因位点的研究与应用[J]. 浙江农业学报, 1999, 11(5):266. [6] 江玲霞, 李纪委, 贺彧, 等. Sox基因家族功能的研究进展[J]. 生物技术通报, 2008(6):44-48. [7] Chiang EF, Pai CI, Wyatt M, et al. Two Sox9 genes on duplicated zebrafish chromosomes:Expression of similar transcription activators in distinct sites[J]. Developmental Biology, 2001, 231(1):149-163. [8] 杜启艳, 常重杰, 王凤羽, 等.鲤鱼中Sox9b基因的克隆和表达[J]. 实验生物学报, 2005, 38(5):35-41. [9] Kobayashi T, Kajiura-Kobayashi H, Guan G, et al. Sexual dimorphic expression of DMRT1 and Sox9a during gonadal differentiation and hormone-induced sex reversal in the teleost fish nile tilapia(Oreochromis niloticus)[J]. Developmental Dynamics, 2008, 237(1):297-306. [10] 曾宣, 施志仪, 陈晓武, 等.褐牙鲆变态期间骨骼发育及其相关基因Sox9, Bmp4和Bmp2的表达分析[J]. 海洋渔业, 2009, 31(4):337-346. [11] Yokoi H, Kobayashi T, Tanaka M, et al. Sox9 in a teleost fish, medaka(Oryzias latipes):Evidence for diversified function of Sox9 in gonad differentiation[J]. Molecular Reproduction and Development, 2002, 63(1):5-16. [12] 陈金平, 袁红梅, 王斌, 等.史氏鲟Sox9基因cDNA的克隆及在早期发育过程不同组织中的表达[J]. 动物学研究, 2004, 25(6):527-533. [13] 曹谨玲, 陈剑杰, 甘西, 等.鱼类DMRT基因的研究进展[J]. 广东海洋大学学报, 2011, 31(1):94-98. [14] Marchand O, Govoroun M, D'cotta H, et al. DMRT1 expression during gonadal differentiation and spermatogenesis in the rainbow trout, Oncorhynchus mykiss[J]. Biochimica et Biophysica Acta, 2000, 1493(1-2):180-187. [15] 杨东, 余来宁. 尼罗罗非鱼Dmrt1基因克隆及在不同组织中的表达[J]. 湖北农业科学, 2008, 47(7):754-757. [16] 曹谨玲, 曹哲民, 吴婷婷. 奥利亚罗非鱼DMRT1和DMRT4抗体制备及组织表达谱分析[J]. 遗传学报, 2007, 34(6):497-509. [17] 文爱韵, 尤锋, 孙鹏, 等.牙鲆dmrt1基因的克隆及其与P450arom基因的组织表达分析[J]. 海洋科学, 2010, 34(11):97-102. [18] Guo YQ, Cheng HH, Huang X, et al. Gene structure, multiple alternative splicing, and expression in gonads of zebrafish Dmrt1 [J]. Biochemical and Biophysical Research Communications, 2005, 330(3):950-957. [19] Kondo M, Froschauer A, Kitano A, et al. Molecular cloning and characterization of DMRT genes from the medaka Oryzias latipes and the platyfish Xiphophorus maculatus[J]. Gene, 2002, 295(2):213-222. [20] 郭一清. 斑马鱼Dmrt1和Dmrt5基因克隆和表达分析[D]. 武汉:武汉大学, 2004. [21] Matsuda M, Nagahama Y, Shinomiya A, et al. DMY is a Y-specific DM-domain gene required for male development in the medaka fish[J]. Nature, 2002, 417(6888):559-563. [22] Kobayashi T, Matsuda M, Kajiura-Kobayashi H, et al. Two DM domain genes, DMY and DMRT1, involved in testicular differentiation and development in the medaka, Oryzias latipes[J]. Developmental Dynamics, 2004, 231(3):518-526. [23] Matsuda M, Sato T, Toyazaki Y, et al. Oryzias curvinotus has DMY, a gene that is required for male development in the medaka, O. latipes[J]. Zoological Science, 2003, 20(2):159-161. [24] Volff JN, Kondo M, Schartl M. Medaka dmY/dmrt1Y is not the universal primary sex-determining gene in fish[J]. Trends in Genetics, 2003, 19(4):196-199. [25] Visser JA, Themmen APN. Anti-Mullerian hormone and folliculogenesis[J]. Molecular and Cellular Endocrinology, 2005, 234(1-2):81-86. [26] Miura T, Miura C, Konda Y, et al. Spermatogenesis-preventing substance in Japanese eel[J]. Development, 2002, 129(11):2689-2697. [27] 刘姗姗, 孙冰, 梁卓, 等.半滑舌鳎抗缪勒氏管激素(AMH)基因的克隆及组织表达分析[J]. 中国水产科学, 2013, 20(1):35-43. [28] Hattori RS, Murai Y, Oura M, et al. A Y-linked anti-Müllerian hor- mone duplication takes over a critical role in sex determination[J]. Proc Nat Acad Sci USA, 2012, 109(8):2955-2959. [29] Piferrer F, Zanuy S, Carrillo M, et al. Brief treatment with an aromatase inhibitor during sex differentiation causes chromosomally female salmon to develop as normal, functional males[J]. Journal of Experimental Zoology, 1994, 270(3):255-262. [30] Diotel N, Le Page Y, Mouriec K, et al. Aromatase in the brain of teleost fish:Expression, regulation and putative functions[J]. Frontiers in Neuroendocrinology, 2010, 31(2):172-192. [31] Callard GV, Tchoudakova AV, Kishida M, et al. Differential tissue distribution, developmental programming, estrogen regulation and promoter characteristics of cyp19 genes in teleost fish[J]. Journal of Steroid Biochemistry and Molecular Biology, 2001, 79(1-5):305-314. [32] Guiguen Y, Fostier A, Piferrer F, et al. Ovarian aromatase and estr-ogens:A pivotal role for gonadal sex differentiation and sex change in fish[J]. Gen Comp Endocrinol, 2010, 165(3):352-366. [33] Lee BY, Kocher TD. Exclusion of Wilms tumour(WT1b)and ovariancytochrome P450 aromatase(CYP19A1)as candidates for sex determination genes in Nile tilapia(Oreochromis niloticus)[J]. Animal Genetics, 2007, 38(1):85-86. [34] Wang ZJ, Jeffs B, Ito M, et al. Aromatase(Cyp19)expression is up-regulated by targeted disruption of Dax1[J]. Proc Nat Acad Sci USA, 2001, 98(14):7988-7993. [35] Tong SK, Chung BC. Analysis of zebrafish cyp19 promoters[J]. J Steroid Biochem Mol Biol, 2003, 86(3-5):381-386. [36] Yamaguchi T, Yamaguchi S, Hirai T, et al. Follicle-stimulating hormone signaling and Foxl2 are involved in transcriptional regulation of aromatase gene during gonadal sex differentiation in Japanese flounder, Paralichthys olivaceus[J]. Biochemical and Biophysical Research Communications, 2007, 359(4):935-940. [37] Von Schalburg KR, Yasuike M, Yazawa R, et al. Regulation and expression of sexual differentiation factors in embryonic and extragonadal tissues of Atlantic salmon[J]. BMC Genomics, 2011, 12(1):31. [38] Ospina-Alvarez N, Piferrer F. Temperature-dependent sex determination in fish revisited:prevalence, a single sex ratio response pattern, and possible effects of climate change[J]. Plos One, 2008, 3(7):e2837. [39] Vandeputte M, Dupont-Nivet M, Chavanne H, et al. A polygenic hypothesis for sex determination in the European sea bass-Dicentrarchus labrax[J]. Genetics, 2007, 176(2):1049-1057. [40] Liew WC, Bartfai R, Lim Z, et al. Polygenic sex determination system in zebrafish[J]. Plos One, 2012, 7(4):e34397. [41] Moriyama S, Ayson FG, Kawauchi H. Growth regulation by insulin-like growth factor-I in fish[J]. Biosci Biotechnol Biochem, 2000, 64(8):1553-1562. [42] Butler AA, Le Roith D. Control of growth by the somatropic axis:growth hormone and the insulin-like growth factors have related and independent roles[J]. Annual Review of Physiology, 2001, 63:141-64. [43] 李文笙, 林浩然. 鱼类生长激素合成与分泌的内分泌调控网络:垂体生长激素分泌细胞中的信号整合[J]. 中国科学:生命科学, 2010(2):149-158. [44] 匡刚桥, 刘臻, 鲁双庆. 鱼类生长激素基因的研究现状及展望[J]. 水利渔业, 2006(6):1-3. [45] Moriyama S, Yamamoto H, Sugimoto S, et al. Oral administration of recombinant salmon growth hormone to rainbow trout, Oncorhynchus mykiss[J]. Aquaculture, 1993, 112(1):99-106. [46] 赵晓祥, 张淑梅. 鲤鱼生长激素基因在鲫鱼中的基因转移及 PCR 检测[J]. 发育与生殖生物学报, 1996, 5(2):34-40. [47] 刘峰, 鲁双庆, 刘臻, 等.三种鳜鱼(Siniperca)生长激素基因内含子多态性的比较研究[J]. 海洋与湖沼, 2009(4):470-478. [48] 倪静, 尤锋, 张培军, 等.牙鲆GH基因外显子多态性与生长性状关系的初步研究[J]. 高技术通讯, 2006, 16(3):307-312. [49] 倪静, 尤锋, 于深辉, 等.牙鲆GHR基因Promoter区微卫星序列多态性与生长性状关系的初步研究[J]. 中国海洋大学学 报:自然科学版, 2008, 28(5):719-725. [50] 陶文静, 马龙俊, 阮瑞霞, 等.建鲤GHR基因多态性及与增重相关的SNP位点的筛选[J]. 水生生物学报, 2011(4):622-629. [51] Mayo KE, Godfrey PA, Suhr ST, et al. Growth hormone-releasing hormone:synthesis and signaling[J]. Recent Prog Horm Res, 1995, 50:35-73. [52] Mayo KE, Cerelli GM, Lebo RV, et al. Gene encoding human growth hormone-releasing factor precursor:structure, sequence, and chromosomal assignment[J]. Proceedings of the National Academy of Sciences, 1985, 82(1):63-67. [53] Tao WJ, Boulding EG. Associations between single nucleotide polymorphisms in candidate genes and growth rate in Arctic charr(Salvelinus alpinus L.)[J]. Heredity, 2003, 91(1):60-69. [54] 冯科, 张桂蓉, 魏开建, 等.鱼类生长激素释放肽及其受体的研究进展[J]. 湖北农业科学, 2013(3):497-501, 513. [55] Kaiya H, Miyazato M, Kangawa K, et al. Ghrelin:a multifunctional hormone in non-mammalian vertebrates[J]. Comp Biochem Physiol A Mol Integr Physiol, 2008, 149(2):109-28. [56] Jonsson E. The role of ghrelin in energy balance regulation in fish[J]. Gen Comp Endocrinol, 2013, 187:79-85. [57] 刘军, 陈爱敬, 胡先勤, 等.饥饿素对鲫鱼生长性能的影响[J]. 中国饲料, 2012, (21):30-32. [58] Amole N, Unniappan S. Fasting induces preproghrelin mRNA expression in the brain and gut of zebrafish, Danio rerio[J]. Gen Comp Endocrinol, 2009, 161(1):133-137. [59] Ping HC, Feng K, Zhang GR, et al. Ontogeny expression of ghrelin, neuropeptide Y and cholecystokinin in blunt snout bream, Megalobrama amblycephala[J]. J Anim Physiol Anim Nutr, doi:10.1111/jpn.12084. [60] Feng K, Zhang GR, Wei KJ, et al. Molecular cloning, tissue distribution, and ontogenetic expression of ghrelin and regulation of expression by fasting and refeeding in the grass carp(Ctenophary-ngodon idellus)[J]. J Exp Zool A Ecol Genet Physiol, 2013, 319(4):202-212. [61] Suda A, Kaiya H, Nikaido H, et al. Identification and gene expression analyses of ghrelin in the stomach of Pacific bluefin tuna(Thunnus orientalis)[J]. Gen Comp Endocrinol, 2012, 178(1):89-97. [62] 叶星, 李文笙, 林浩然. 鱼类生长抑素及其受体的研究进展[J]. 水产学报, 2007, 31(2):264-272. [63] Sheridan MA, Hagemeister AL. Somatostatin and somatostatin receptors in fish growth[J]. Gen Comp Endocrinol, 2010, 167(3):360-365. [64] Lin X, Peter RE. Somatostatin-like receptors in goldfish:cloning of four new receptors[J]. Peptides, 2003, 24(1):53-63. [65] Slagter BJ, Sheridan MA. Differential expression of two somatostatin receptor subtype 1 mRNAs in rainbow trout(Oncorhynchus mykiss)[J]. J Mol Endocrinol, 2004, 32(1):165-177. [66] 肖东, 林浩然. 鱼类垂体腺苷酸环化酶激活多肽的研究进展[J]. 水生生物学报, 2003, 27(3):296-301. [67] Montero M, Yon L, Kikuyama S, et al. Molecular evolution of the growth hormone-releasing hormone/pituitary adenylate cyclase-activating polypeptide gene family. Functional implication in the regulation of growth hormone secretion[J]. J Mol Endocrinol, 2000, 25(2):157-168. [68] Sze KH, Zhou H, Yang Y, et al. Pituitary adenylate cyclase-activating polypeptide(PACAP)as a growth hormone(GH)-releasing factor in grass carp:II. Solution structure of a brain-specific PACAP by nuclear magnetic resonance spectroscopy and functional studies on GH release and gene expression[J]. Endocrinology, 2007, 148(10):5042-5059. [69] Lugo JM, Rodriguez A, Helguera Y, et al. Recombinant novel pituitary adenylate cyclase-activating polypeptide from African catfish(Clarias gariepinus)authenticates its biological function as a growth-promoting factor in low vertebrates[J]. J Endocrinol, 2008, 197(3):583-597. [70] Pedrazzini T, Pralong F, Grouzmann E. Neuropeptide Y:the universal soldier[J]. Cell Mol Life Sci, 2003, 60(2):350-377. [71] Miura T, Maruyama K, Shimakura S, et al. Neuropeptide Y mediates ghrelin-induced feeding in the goldfish, Carassius auratus[J]. Neurosci Lett, 2006, 407(3):279-283. [72] Zhou Y, Liang XF, Yuan X, et al. Neuropeptide Y stimulates food intake and regulates metabolism in grass carp, Ctenopharyngodon idellus[J]. Aquaculture, 2013, 380:52-61. [73] Ma XL, Zheng LW, Mao LT, et al. Neuropeptide Y in black seabream Acanthopagrus schlegelii:identification, distribution and mRNA expression responses to ghrelin[J]. Journal of Fish Biology, 2013, 82(4):1441-1447. [74] 徐芃. 牙鲆成肌因子myogenin和MRF4的研究[D]. 青岛:中国科学院研究生院, 2007. [75] 张玉青. 牙鲆肌肉发育调节基因的克隆、表达及功能分析[D]. 青岛:中国科学院研究生院, 2008. [76] 于凌云, 白俊杰, 叶星, 等.大口黑鲈MyoD基因结构和单核苷酸多态性位点的筛选[J]. 水产学报, 2009(1):1-8. [77] 于凌云, 白俊杰, 樊佳佳, 等.大口黑鲈肌肉生长抑制素基因单核苷酸多态性位点的筛选及其与生长性状关联性分析[J]. 水产学报, 2010, 34(6):665-671. [78] 钟茂春, 郑光明, 赵建, 等.鲮Myf5基因克隆及其SNPs分析[J]. 中国水产科学, 2010(4):681-688. [79] Castillo J, Codina M, Martínez ML, et al. Metabolic and mitogenic effects of IGF-I and insulin on muscle cells of rainbow trout[J]. Ame J Physiol Regul Integr Comp Physiol, 2004, 286(5):R935-R941. [80] Wilson EM, Hsieh MM, Rotwein P. Autocrine growth factor signaling by insulin-like growth factor-II mediates MyoD-stimulated myocyte maturation[J]. Journal of Biological Chemistry, 2003, 278(42):41109-41113. [81] 阮瑞霞, 俞菊华, 李红霞, 等.吉富罗非鱼IGF-1基因的基因型对生长和体型的影响[J]. 中国水产科学, 2011, 18(3):682-688. [82] 陈雪峰, 杨国梁, 俞菊华, 等.吉富罗非鱼IGF2基因分离及其单核苷酸多态性与体型、增重相关性[J]. 动物学杂志, 2010(2):107-114. [83] 杨建宝. 甘肃金鳟部分形态性状对体质量的影响以及IGF-Ⅰ、IGF-Ⅱ基因的SNPs与生长性状的关联分析[D]. 兰州:甘肃农业大学, 2012. [84] 张殿昌. 鱼类胰岛素样生长因子研究进展[J]. 上海水产大学学报, 2005, 14(1):66-71. [85] Jones JI, Clemmons DR. Insulin-like growth factors and their binding proteins:biological actions[J]. Endocr Rev, 1995, 16(1):3-34. [86] Hwa V, Oh Y, Rosenfeld RG. The insulin-like growth factor-binding protein(IGFBP)superfamily[J]. Endocr Rev, 1999, 20(6):761-87. [87] 陈文波. 鲤鱼类胰岛素生长因子结合蛋白(IGFBP)-1、-2和-3基因的克隆及其表达调控机制研究[D]. 广州:中山大学, 2009. [88] 陶洋, 邹曙明. 草鱼胰岛素样生长因子结合蛋白IGFBP-1基因的全长cDNA克隆及表达[J]. 上海海洋大学学报, 2011, 20(1):15-21. [89] 翟万营. 牙鲆IGFBP-1、HIF-1α基因的克隆及功能研究[D].上海:上海海洋大学, 2012. [90] 魏可鹏, 俞菊华, 李红霞, 等.建鲤IGFBP3基因多态性对生长的影响[J]. 动物学杂志, 2012, 47(1):96-104. [91] Mcpherron AC, Lawler AM, Lee SJ. Regulation of skeletal muscle mass in mice by a new TGF-beta superfamily member[J]. Nature, 1997, 387(6628):83-90. [92] Acosta J, Carpio Y, Borroto I, et al. Myostatin gene silenced by RNAi show a zebrafish giant phenotype[J]. Journal of Biotechnology, 2005, 119(4):324-331. [93] 李西, 聂芬, 殷战, 等.转基因高表达卵泡抑素 1 对斑马鱼肌肉生长促进作用研究[J]. 中国科学:生命科学, 2011, 41(1):53-60. [94] 杨斌, 薛良义, 叶秀丽, 等.大黄鱼肌肉生长抑制素基因外显子Ⅱ遗传多态性分析[J]. 海洋通报, 2010(5):554-559. [95] 薛良义, 孙升, 肖章奎, 等.大黄鱼肌肉生长抑制素基因微卫星序列多态性分析[J]. 中国生物化学与分子生物学报, 2008(10):980-985. [96] 唐永凯, 李建林, 俞菊华, 等.吉富罗非鱼MSTN基因结构及其多态性与生长性状的相关性[J]. 中国水产科学, 2010(1):44-51. [97] 朱媛媛, 梁宏伟, 李忠, 等.黄颡鱼MSTN基因多态性及其与生长性状的相关性分析[J]. 遗传, 2012(1):74-80. [98] Chen AS, Metzger JM, Trumbauer ME, et al. Role of the melanocortin-4 receptor in metabolic rate and food intake in mice[J]. Transgenic Research, 2000, 9(2):145-154. [99] 刘福平, 白俊杰, 叶星, 等.罗非鱼MC4R基因克隆及与其生长相关的SNPs位点[J]. 中国水产科学, 2009(6):816-823. [100] 农小献, 宾石玉, 蒙涛, 等.小清蛋白研究进展[J]. 生物技术通讯, 2011, 22(6):887-891. [101] Xu YX, Zhu ZY, Lo LC, et al. Characterization of two parvalbumin genes and their association with growth traits in Asian seabass(Lates calcarifer)[J]. Animal Genetics, 2006, 37(3):266-268. [102] 陈芳芳, 潘玲, 耿照玉, 等. MHC分子多态性的起源、演变与抗病机理[J]. 畜牧兽医学报, 2010(9):1061-1067. [103] Palti Y, Nichols KM, Waller KI, et al. Association between DNA polymorphisms tightly linked to MHC class II genes and IHN virus resistance in backcrosses of rainbow and cutthroat trout[J]. Aquaculture, 2001, 194(3-4):283-289. [104] Rakus KL, Wiegertjes GF, Jurecka P, et al. Major histocompatibi-lity(MH)class II B gene polymorphism influences disease resistance of common carp(Cyprinus carpio L.)[J]. Aquacult-ure, 2009, 288(1-2):44-50. [105] Grimholt U, Larsen S, Nordmo R, et al. MHC polymorphism and disease resistance in Atlantic salmon(Salmo salar);facing pathogens with single expressed major histocompatibility class I and class II loci[J]. Immunogenetics, 2003, 55(4):210-219. [106] 周芬娜. 尼罗罗非鱼MHC基因的克隆、表达及多态性研究[D]. 济南:山东农业大学, 2012. [107] 张玉喜, 陈松林. 牙鲆MHC class ⅡB基因多态性及其与鱼体抗病力关系的分析[J]. 水产学报, 2006, (05):633-639. [108] Clemens MJ, Elia A. The double-stranded RNA-dependent protein kinase PKR:structure and function[J]. J Interferon Cytokine Res, 1997, 17(9):503-524. [109] 彭梧, 汤雅男, 胡成钰, 彭汤. CaPKR-like在鲫鱼与草鱼组织中的表达特性分析[J]. 动物学研究, 2007, 28(5):465-469. [110] 李景芬, 刘莉, 曹访. PolyI:C体外诱导草鱼PKR基因的克隆与表达[J]. 安徽农业科学, 2011, (33):20514-20516, 20529. [111] Haase AD, Jaskiewicz L, Zhang H, et al. TRBP, a regulator of cellular PKR and HIV-1 virus expression, interacts with Dicer and functions in RNA silencing[J]. EMBO Rep, 2005, 6(10):961-967. [112] Wang S, Liu N, Chen AJ, et al. TRBP homolog interacts with eukaryotic initiation factor 6(eIF6)in Fenneropenaeus chinensis[J]. J Immunol, 2009, 182(9):5250-5258. [113] 周联, 俞瑜. 防御素与先天性免疫及获得性免疫[J]. 国外医学:免疫学分册, 2005, 28(2):68-72. [114] 金俊琰, 周莉, 桂建芳. 石斑鱼β-防御素的酵母表达及其产物抗菌活性分析[J]. 水生生物学报, 2011(5):739-744. [115] 史玉婷. 草鱼肠道β-防御素克隆表达及抗菌活性分析[D]. 长沙:湖南农业大学, 2012. [116] 李怡, 张令强, 贺福初. 病毒感染和免疫清除中的C型凝集素[J]. 生命的化学, 2005(4):281-284. [117] 陈聪, 姜北, 万瑛. 模式识别受体视黄酸诱导基因-Ⅰ样受体及信号通路研究进展[J]. 免疫学杂志, 2010(7):636-638. [118] 黄腾. 草鱼MDA5基因和LGP2基因的克隆与表达[D]. 杨 凌:西北农林科技大学, 2010. [119] 钟其旺, 樊廷俊. 鱼类抗冻蛋白的研究进展[J]. 生物化学与生物物理学报, 2002(2):124-130. [120] 张晓, 吴海珍, 卫玮, 等.大黄鱼类Ⅳ型抗冻蛋白基因的克隆、表达及功能研究[J]. 食品与药品, 2009(9):15-19. [121] 彭金霞, 殷勤, 崔亮, 等.凡纳滨对虾TCP-1-Beta基因的克隆及其与耐寒性状的相关性[J]. 水生生物学报, 2011, 35(4):604-609. [122] 殷勤, 彭金霞, 崔亮, 等.凡纳滨对虾TCP-1-eta基因的克隆及与耐寒性状的相关性[J]. 遗传, 2011(2):168-174. [123] Wu RS, Zhou BS, Randall DJ, et al. Aquatic hypoxia is an endocrine disruptor and impairs fish reproduction[J]. Environ Sci Technol, 2003, 37(6):1137-1141. [124] Chiarugi V, Magnelli L, Chiarugi A, et al. Hypoxia induces pivotal tumor angiogenesis control factors including p53, vascular endothelial growth factor and the NFkB-dependent inducible nitric oxide synthase and cyclooxygenase-2[J]. Journal of Cancer Research and Clinical Oncology, 1999, 125(8-9):525-528. [125] 张鹏华, 陈兰英. 低氧诱导因子-1的转录活性调控及其信号传导[J]. 生物化学与生物物理进展, 2002, 29(6):863-867. [126] Zhang YB, Gui HF. Identification and expression analysis of two IFN-inducible genes in crucian carp(Carassius auratus L.)[J]. Gene, 2004, 325:43-51. [127] 龙华, 曾勇, 李谷. 鱼类血清转铁蛋白的研究现状与应用前景[J]. 水产学报, 2001, 25(2):181-186. [128] 龙华, 刘曼西. 淡水养殖鱼类血清转铁蛋白耐低氧特性的研究[J]. 华中理工大学学报, 2000(1):85-88. [129] 龙华, 汤伏生, 曾勇, 等.淡水鱼类血清转铁蛋自遗传多态性研究[J]. 水产学报, 1996(2):168-174. [130] 李明云, 张春丹. 四种海水养殖鱼类血清转铁蛋白多态性的初步研究[J]. 科技通报, 2009(6):753-757. [131] Kajimura S, Aida K, Duan C. Understanding hypoxia-induced gene expression in early development:in vitro and in vivo analysis of hypoxia-inducible factor 1-regulated zebra fish insulin-like growth factor binding protein 1 gene expression[J]. Molecular and Cellular Biology, 2006, 26(3):1142-1155. [132] 陶洋. 草鱼低氧调控IGFBP-1cDNA的克隆与功能研究[D]. 上海:上海海洋大学, 2010. [133] 丁为群, 梁宏伟, 邹桂伟, 等.鲢IGFBP-1基因全长cDNA的克隆及表达分析[J]. 西北农林科技大学学报:自然科学版, 2013(5):1-8. [134] 仝颜娜, 孔祥会, 江红霞. 鱼类血红素加氧酶-1的功能及表达调控研究进展[J]. 生物学教学, 2011(12):2-3. [135] Wang D, Zhong XP, Qiao ZX, et al. Inductive transcription and protective role of fish heme oxygenase-1 under hypoxic stress[J]. Journal of Experimental Biology, 2008, 211(16):2700-2706. [136] 桂建芳, 朱作言. 水产动物重要经济性状的分子基础及其遗传改良[J]. 科学通报, 2012, 57(19):1719-1729. |
[1] | 肖亮, 吴正丹, 陆柳英, 施平丽, 尚小红, 曹升, 曾文丹, 严华兵. 木薯重要性状基因的研究进展[J]. 生物技术通报, 2023, 39(6): 31-48. |
[2] | 赵海晴, 李耘, 梁严内, 刘哲, 任亚林, 李金娟. 联合用药对嗜水气单胞菌耐药性影响研究进展[J]. 生物技术通报, 2022, 38(6): 53-65. |
[3] | 田李, 李俊娇, 戴小枫, 张丹丹, 陈捷胤. 从功能基因到生物学性状:大丽轮枝菌致病性形成的分子基础[J]. 生物技术通报, 2022, 38(1): 51-69. |
[4] | 江迪, 徐春城. 发酵TMR应用及其微生物种群演替规律研究进展[J]. 生物技术通报, 2021, 37(9): 31-38. |
[5] | 张颖超, 尹守亮, 王一炜, 王学凯, 杨富裕. 木本饲料青贮研究进展[J]. 生物技术通报, 2021, 37(9): 48-57. |
[6] | 高鹏飞, 席飞虎, 张泽宇, 胡凯强, 陈凯, 魏文桃, 丁家治, 顾连峰. 植物VIGS技术及其在林业科学中的研究进展[J]. 生物技术通报, 2021, 37(5): 141-153. |
[7] | 潘银来, 邱春辉, 王艺磊, 张子平. RNA药物的发展及其在水产上的应用[J]. 生物技术通报, 2021, 37(2): 203-215. |
[8] | 陈一丹, 张昱, 杨洁, 张勤, 姜力. 基于转录组测序的奶牛产奶性状重要功能基因挖掘[J]. 生物技术通报, 2020, 36(9): 244-252. |
[9] | 宋华丽, 孙效迎, 孔祥会, 李莉, 裴超. RNA干扰技术在水产动物抗病毒和抗寄生虫研究中的应用研究进展[J]. 生物技术通报, 2020, 36(2): 193-205. |
[10] | 张海淼, 李洋, 刘海峰, 孔令广, 丁新华. 水稻重要农艺性状调控基因及其育种利用研究进展[J]. 生物技术通报, 2020, 36(12): 155-169. |
[11] | 李锐, 孙祖莉, 杨贤庆, 李来好, 魏涯, 岑剑伟, 王晶, 赵永强. 代谢组学在水产品品质与安全中的研究进展[J]. 生物技术通报, 2020, 36(11): 155-163. |
[12] | 李慧, 查建军, 孙庆业. 酸性矿业废水对土壤剖面中氮代谢功能基因丰度的影响[J]. 生物技术通报, 2019, 35(9): 249-256. |
[13] | 吴琴琴, 孙敏, 陈雨, 付雅琴, 曾斌, 贺斌. 米曲霉功能基因组研究策略和进展[J]. 生物技术通报, 2019, 35(8): 186-192. |
[14] | 朱荣贵, 关统伟, 姜秀娟. 塔里木盆地5个生态小区稀有放线菌分离及合成抗生素基因分布[J]. 生物技术通报, 2018, 34(9): 230-236. |
[15] | 李晓凯 ,王贵 ,乔贤 ,范一星 ,张磊 ,马宇浩 ,聂瑞雪 ,王瑞军 ,何利兵 ,苏蕊. 全基因组测序在重要家畜上的研究进展[J]. 生物技术通报, 2018, 34(6): 11-21. |
阅读次数 | ||||||
全文 |
|
|||||
摘要 |
|
|||||