生物技术通报 ›› 2015, Vol. 31 ›› Issue (8): 24-29.doi: 10.13560/j.cnki.biotech.bull.1985.2015.08.004

• 综述与专论 • 上一篇    下一篇

鹿茸再生相关蛋白研究进展

王权威, 董振, 王桂武, 杨福合, 刘慧, 李春义   

  1. 中国农业科学院特产研究所 特种动物分子生物学国家重点实验室,长春 130112
  • 收稿日期:2014-11-03 出版日期:2015-08-21 发布日期:2015-08-22
  • 作者简介:王权威,男,硕士研究生,研究方向:鹿茸干细胞膜蛋白质组学;;E-mail:wangquanwei@yahoo.com
  • 基金资助:
    国家科技支撑计划(2011BAI03B02),国家“973”计划(2012CB722907),吉林省自然科学基金项目(201115129),吉林省科技支撑重点项目(20120965)

Research Progress on Proteins Related to Deer Antler Regeneration

Wang Quanwei, Dong Zhen, Wang Guiwu, Yang Fuhe, Liu Hui, Li Chunyi   

  1. State Key Lab for Molecular Biology of Special Animals/Institute of Special Animal and Plant Sciences,Chinese Academy of Agricultural Science,Changchun 130112
  • Received:2014-11-03 Published:2015-08-21 Online:2015-08-22

摘要: 鹿茸是迄今为止发现的唯一能够周期性再生的哺乳动物器官,它的生长速度极快却没有发生癌变。而蛋白质是生命活动的体现者,是生命活动的功能执行者,鹿茸相关蛋白的研究是揭开鹿茸再生秘密的重要途径。综述了鹿茸再生相关蛋白的筛选、血管生成相关蛋白、软骨形成相关蛋白、神经再生相关蛋白以及其他与鹿茸再生相关蛋白的研究进展,旨在为从蛋白质水平上揭示鹿茸再生过程提供基础资料。

关键词: 鹿茸再生相关蛋白, 血管生成, 软骨形成, 神经再生

Abstract: Deer antler is an only known mammalian organ that can periodically regenerate, and grow very rapidly without going cancerous. Proteins are the carrier and the function executor of life activities, the research of proteins related to deer antler is an important measure to unlock the secrets of antler’s regeneration. The proteins involved in angiogenesis, cartilage formation, nerve regeneration and other functions during antler regeneration are reviewed which aims at providing basic data for revealing antler regeneration process at the protein level.

Key words: proteins related to deer antler regeneration, angiogenesis, cartilage formation, nerve regeneration