光及光热纳米材料在生物传感、药物靶向运输和生物成像中的应用

doi:10.13560/j.cnki.biotech.bull.1985.2018-0388

摘要/Abstract

摘要： 纳米材料是纳米科学技术的重要发展方向之一。纳米材料的结构赋予了其独特的光学性质,纳米尺寸方便其经EPR效应或表面修饰靶向肿瘤组织,并且部分纳米材料可吸收外部光源能量,将其转化为热能。因此,纳米材料在光学传感器、生物成像、药物靶向运输及肿瘤光热治疗中的应用十分广泛。综述主要分类介绍了光学纳米材料和光热纳米材料的优异特性,阐述了其在以上领域中的应用;最后,对纳米材料未来的发展作出了展望。

关键词: 光学纳米材料, 光热纳米材料, 光学生物传感器, 生物成像, 药物靶向运输, 光热治疗

Abstract: Nanomaterials are one of the important development directions in nano-science and technology. The structure of nanomaterials has endowed it unique optical properties,the nanometer size facilitates its targeting to tumor tissue via EPR effect or surface modification,and some nanomaterials can absorb the energy of an external light source and convert it into heat energy. Therefore,nanomaterials are widely applied in optical sensors,bioimaging,drug-targeted delivery,and tumor photothermal therapy. This review mainly describes the excellent properties of optical nanomaterials and photothermal nanomaterials,and illuminates their applications in the above fields. Finally,the future development trend of nanomaterials is prospected.

Key words: optical nanomaterials, photothermal nanomaterials, optical biosensors, bioimaging, drug-targeted delivery, phototherapy

郑力榕, 罗云波, 许文涛. 光及光热纳米材料在生物传感、药物靶向运输和生物成像中的应用[J]. 生物技术通报, 2018, 34(9): 79-89.

ZHENG Li-rong, LUO Yun-bo, XU Wen-tao. Applications of Optical and Photothermal Nanomaterials in Biosensing,Drug-targeted Delivery and Bioimaging[J]. Biotechnology Bulletin, 2018, 34(9): 79-89.

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