Biotechnology Bulletin ›› 2015, Vol. 31 ›› Issue (11): 68-77.doi: 10.13560/j.cnki.biotech.bull.1985.2015.11.004

• Review • Previous Articles     Next Articles

Classification, Prediction and Database Construction of Plant Transcription Factors

Jin Jinpu1, Guo Anyuan1,2, He Kun1,3, Zhang He1,4, Zhu Qihui1,5, Chen Xin1, Gao Ge1, Luo Jingchu1   

  1. 1. College of Life Sciences,the State Key Laboratory of Protein and Plant Gene Research,Center for Bioinformatics, Peking University,Beijing 100871;2. College of Life Science and Technology,Huazhong University of Science and Technology,Wuhan 430074;3. Monsanto Company,USA;4. University of Michigan,USA;5. The Jackson Laboratory for Genomic Medicine, USA
  • Received:2015-10-31 Online:2015-11-26 Published:2015-11-26

Abstract: Transcription factors(TFs)play key regulatory roles in both plant development and stress response. Genome-wide prediction of TFs is essential for functional and evolutionary studies of plant TFs. We made extensive literature review with thousands papers related to plant TFs and summarized a set of classification rules for plant TFs and developed a TF prediction pipeline. Using this pipeline, we predicted 129 288 TFs, classified into 58 families, from 83 plant species covering the main lineages of green plants including many economically important monocot and dicot crops. We made high-quality annotations for these TFs and built a plant TF database PlantTFDB(http: //planttfdb.cbi.pku.edu.cn). A TF prediction server was also developed for users to predict TFs from their own sequences. PlantTFDB has been served as an important portal for the functional and evolutionary studies of plant TF research community.

Key words: transcription factor, classification of transcription factor, prediction of transcription factor, plant transcription factor database