Research Progress on Biological Effect of Endosulfan

Abstract

Abstract: Endosulfan is a class of persistent organic pollutants (POPs), implicated in a variety of human diseases with widespread concern. Endosulfan has been added to Annex A of the Stockholm Convention in 2011, but the impact of endosulfan on the environment and human health still should not be ignored by people. Endosulfan might affect environment and human health for a long time due to its characteristics of the environmental behavior including persistence, bioconcentration and high biological toxicity, as well as potential carcinogenicity, mutagenicity and endocrine disruptor effects. Here, we summarize the recent research overviews on environmental behavior, biological toxicity and harm to human. Especially, we focus on cytotoxicity of endosulfan to collect, sort out and perform further analysis, followed by valuable suggestion about future direction of research work. Hopefully, this review will be helpful to understand the reason that endosulfan is disabled nowadays and provide new idea of revealing the mechanism in biological effects of POPs including endosulfan.

Key words: Endosulfan, Persistent organic pollutants, Biological toxicity, Carcinogenicity, Mutagenicity, Endocrine disruptor

Xu Dan, Li Shuai, Zhang Min, Sun Yeqing. Research Progress on Biological Effect of Endosulfan[J]. Biotechnology Bulletin, 2013, 0(5): 45-51.

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