Research Advance of the Construction of Gene Engineering Strains for Glucosamine

Abstract

Abstract: Glucosamine(GlcN), also called amino sugar, was a compound derived from the substitution of a hydroxyl group of glucose molecule with an amino group. GlcN found a wide-range of applications in health food and pharmaceutical industries. Glucosamine was currently produced by extraction and acid hydrolysis of chitin from shellfish waste, which was limited by the amount of raw material available and existed great risks of environment pollution. However, recombinant strain of gene engineering to overexpress the glucosamine could avoid those problems. the gene engineering strain, its metabolic pathway and fermentation of glucosamine were introduced. It is a great significance to ferment glucosamine and N-acetyglucosamine.

Key words: Glucosamine, N-acetyglucosamine, Gene engineering strain, Fementation

Liu Dianlei, Li Piwu, Li Ruirui, Wang Sheng, Wang Ruiming. Research Advance of the Construction of Gene Engineering Strains for Glucosamine[J]. Biotechnology Bulletin, 2014, 0(3): 36-41.

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