Progress on Antimicrobial Peptides’Gene Endogenous Expression Regulation and Clinical Application

Abstract

Abstract: Antimicrobial peptides are a group of small molecular proteins with antibacterial activities, which are key components of animal and vegetation defense system and play an important role in protecting body from invasion of pathogens. These peptides have many characters such as low molecular weight, thermostability. And they have the wide range of antibacterial, antiviral spectrum and inhibiting growth of tumor cells. However, the development of antimicmbial peptides as antibiotic substitutes is far from easy. The recent warm spots about antimicrobial peptides, especially gene expression regulation and clinical application were reviewed.

Key words: Antimicrobial peptides Ⅲ clinical trials, Gene expression regulation, Development, Strategy

Chen Hongwei, Li Yinglun, Liu Juan, Wu Junwei, Huang Qingzhou,. Progress on Antimicrobial Peptides’Gene Endogenous Expression Regulation and Clinical Application[J]. Biotechnology Bulletin, 2014, 0(4): 25-29.

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