Review on the Immunogenicity of Pathogenic Vibrio Outer Membrane Proteins

Abstract

Abstract: Vibrio is a common opportunistic pathogen in aquaculture environment, which can lead to an outbreak of mass mortality of fish and shellfish farming. Traditional chemical control methods because of drug resistance, drug residues and other issues make Vibriosis prevention face new challenges, and thus how to get safe and effective prevention and treatment of diseases caused by Vibrio becomes important and difficult. Vibrio is Gram-negative bacteria, the outer membrane is unique to the cell wall of this type of bacteria, which consist of protein, sugar and lipid. The outer membrane protein is easy to be recongnized as foreign by the host immune system then stimulate the humoral and cellular immunity, which may be used as an active ingredient of Vibrio vaccines. A review on the immunogenicity of pathogenic Vibrio outer membrane protein is to provide a new solution for the prevention and treatment of Vibriosis.

Key words: Vibrio, Outer membrane proteins, Immunogenicity, Immuno-protection, Cross immuno-protection

Lu Panpan, Guo Songlin, Guan Ruizhang, Feng Jianjun. Review on the Immunogenicity of Pathogenic Vibrio Outer Membrane Proteins[J]. Biotechnology Bulletin, 2014, 0(4): 30-35.

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