A Review of Development in WSSV Immediate-early Gene Research

Abstract

Abstract: White spot syndrome virus is one of the main pathogens which causes great damage to the shrimp aquaculture. During the infection, WSSV immediate-early genes（IE genes）utilize the host cell transcription regulators to increase their own transcription. Regulatory proteins encoded by IE genes are critical for the virus life cycle. The IE proteins may either regulate the expression of viral genes, or interact with regulators in the host cells to create a proper environment for viral replication. Here we reviewed the recent progress in WSSV IE gene research and especially focused on five most-studied WSSV immediate-early genes：ie1, wsv051, wsv083, wsv249 and wsv403. The function of IE proteins and the transcription regulation of their genes were discussed.

Key words: WSSV immediate-early genes, ie1, wsv051, wsv083, wsv249 wsv403

Ran Xiaozhuo, Li Fang. A Review of Development in WSSV Immediate-early Gene Research[J]. Biotechnology Bulletin, 2014, 0(8): 52-58.

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