Biotechnology Bulletin ›› 2017, Vol. 33 ›› Issue (3): 12-21.doi: 10.13560/j.cnki.biotech.bull.1985.2017.03.003

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Research Progress on Tumor Markers by Secretomics

YU Le-zheng, LIU Feng-juan, WU Zheng-yu, RAN Xiao-qiang   

  1. School of Chemistry and Life Science,Guizhou Normal College,Guiyang 550018
  • Received:2016-07-02 Online:2017-03-26 Published:2017-03-07

Abstract: In the occurrence and development processes of tumor,a large number of proteins are secreted by tumor cells,and some of them are considered as tumor markers and used for clinical detection and prognosis. With the rapid development of proteomics techniques,secretomics is born at the right moment and provides new ideas and methods for tumor research. Now the strategy and the advance in the study of tumor markers by secretomics are reviewed,which may provide reference for the researchers in the discovery and screening of tumor markers.

Key words: secreted proteins, secretome, secretomics, tumor markers