Research Progress of Demethylase ROS1 in Plants

doi:10.13560/j.cnki.biotech.bull.1985.2019-1017

Abstract

Abstract: DNA methylation status is the result of de novo synthesis of methylation,maintenance methylation and dynamic demethylation of DNA,and is catalyzed by various regulatory pathways targeting various enzymes. 5-methylcytosine DNA glycosylase/lyase ROS1（Repressor of Silencing1）is a DNA demethylase that can initiate DNA active targeting by initiating a base excision repair pathway. In this review,we describe demethylases and regulatory factors for active DNA demethylation in plants,ROS1-mediated DNA demethylation,the roles of DNA active demethylase ROS1 in different plant development processes,including negative regulation of imprinted gene expression and seed dormancy,regulation of rice grain quality,and affecting plant stomatal development.

Key words: active DNA demethylation, demethylase ROS1, plant development

WANG Jie, XIE Li-nan. Research Progress of Demethylase ROS1 in Plants[J]. Biotechnology Bulletin, 2020, 36(7): 148-157.

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