Research Advance in Genome-wide Identification of Transcription Regulatory Elements

Abstract

Abstract: Expression of eukaryotic genes is a complex process, achieved through the coordinated action of transcription regulatory elements. The screening and identification of transcriptional regulatory elements in genome scale have crucial significance for understanding the mechanism and biological function of gene expression regulation. However, the effectively screening and function verification is still the major challenges for researchers. Herein, based on the latest research findings, we reviewed the methods of prediction, screening, function analysis of transcription regulatory elements in genome.

Key words: Transcriptional regulatory element, High throughput screening, Biomark

Li Wenmao, Jia Dongfang, Xu Rong. Research Advance in Genome-wide Identification of Transcription Regulatory Elements[J]. Biotechnology Bulletin, 2014, 0(10): 64-70.

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