Endocytosis of AtRGS1 Involved in the Regulation of G-protein-mediated Arabidopsis Development and Stress Responses

doi:10.13560/j.cnki.biotech.bull.1985.2021-0849

Abstract

Abstract:

Heterotrimeric G protein complex, classically consisting of Gα,Gβ,and Gγ subunits, mediates an essential signaling pathway across the PM (plasma membrane) in most eukaryotes. In plants, heterotrimeric G proteins regulate multiple biological processes such as plant growth and development, hormones and sugar signal transduction, and defense processes via RGS（regulator of G-protein signaling protein）protein in PM. The endocytosis of PM-localized proteins is involved in the control of their quantity on the PM in response to environmental stimuli and development signals. In Arabidopsis, several studies recently revealed that various external signals induced the endocytosis of AtRGS1, thus promoted the dissociation of AtRGS1 from Gα. Free Gα-GTP,Gβγ subgroup, and internalized AtRGS1 protein could regulate downstream signal transduction, thus affect the corresponding biological processes. In this review, we give an overview of the molecular cytological mechanism of AtRGS1 endocytosis in G-protein-mediated plant development and stress responses in Arabidopsis, aiming to provide a theoretical reference for deep understanding how RGS affects the plants development process and stress responses, as well as shed a new insight on the regulation of signal transduction by endocytosis of PM proteins.

Key words: Arabidopsis, AtRGS1, G proteins, endocytosis, growth and development, stress responses

GU Pan, QI Xue-ying, LI Li, ZHANG Xi, SHAN Xiao-yi. Endocytosis of AtRGS1 Involved in the Regulation of G-protein-mediated Arabidopsis Development and Stress Responses[J]. Biotechnology Bulletin, 2022, 38(6): 34-42.

Figures/Tables 1

References 43

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