Research Progress on Mycoplasma Lipoprotein and Its Variation Interaction with Host

Abstract

Abstract: Lipoproteins are significant structural of mycoplasma, which play an important role in the interactions with host. In recent years there have been many reports proved that lipoproteins may be importantly contributing in the pathogenesis of mycoplasma. In this article describes the characteristic and function of lipoproteins, the role in adherence, the ability leading to inflammatory response and cell apoptosis. Moreover have a review about phase and antigenic variation under the regulation of gene families through ON/OFF molecular switches, size variation, domain shuffling, horizontal gene transfer, and mycoplasmal antigen modulation. As well as the effect of variation of lipoproteins in virulence and the biological significance of diverse surface of mycoplasma also included.

Key words: Mycoplasma, Lipoproteins, Antigenic variation, Surface diversity

Ni Bo, Bai Fangfang, Liu Maojun, Feng Zhixin, Xiong Qiyan, Wei Jianzhong, Shao Guoqing. Research Progress on Mycoplasma Lipoprotein and Its Variation Interaction with Host[J]. Biotechnology Bulletin, 2013, 0(2): 49-54.

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