Caspase-apoptosis Signal Transduction Pathway and Its Research Advance in Aquatic Invertebrates

Abstract

Abstract: Caspases exist in all eukaryotic cells and play important a role in cell apoptosis. They are widely involved in embryonic development, inflammation, organogenesis, metamorphosis, homeostasis and other physiological processes. Caspases transduce signals from outside to the cytoplasm or nucleus by a conserved caspase cascade, hydrolyzing intracellular substrate proteins or activating transcription factors to regulate physiological processes. Currently, most of the knowledge about the mechanisms of the caspase -apoptosis pathway focuses on the mammalian system. So far, basic knowledge of the caspase -apoptosis pathway in aquatic invertebrates is limited. In this article, combined data collected in our laboratory, we reviewed the research advance on caspase-apoptosis pathway in aquatic invertebrates to date.

He Simei Zhang Lili Wang Yilei Wang Guodong. Caspase-apoptosis Signal Transduction Pathway and Its Research Advance in Aquatic Invertebrates[J]. Biotechnology Bulletin, 2013, 0(9): 54-61.

References

[1] Sokolova I. Apoptosis in molluscan immune defense[J].Invertebrate Surviv, 2009, 6：49-58.
[2] Nakajima K, Takahashi A, Yaoita Y. Structure, expression, and function of the Xenopus laevis caspase family[J]. Biol Chem, 2000, 275：10484-10491.
[3] Cohen GM. Caspases：the executioners of apoptosis[J]. Biochem, 1997, 326：1-16.
[4] Philchenkov A. Caspases：potential. targets for. regulating cell death[J]. J Cell Mol Med, 2004, 8（4）432-444.
[5] Yin YB, Zhang Y, Yu P, et al. Comparative study of apoptosis-related gene loci in human, mouse and rat genomes[J]. Acta Biochim Biophys Sin, 2005, 37（5）：341-348.
[6] Eimon PM, Kratz E, Varfolomeev E, et al. Delineation of the cell-extrinsic apoptosis pathway in the zebrafish[J]. Cell Death Differ, 2006, 13（10）：1619-1630.
[7] Kratz E, Eimon PM, Mukhyala K, et al. Functional characterization of the Bcl-2 gene family in the zebrafish[J]. Cell Death Differ, 2006, 13（10）：1631-1640.
[8] Chandra J, Samali A. Triggering and modulation of apoptosis by oxidative stress[J]. Free Radic Biol Med, 2000, 29（3-4）：323.
[9] Wang L, Xu T, Lei WW, et al. Cadmium-induced oxidative stress and apoptotic changes in the testis of freshwater crab, Sinopotamon henanense[J]. PLoS One, 2011, 6（11）：e27853.
[10] Yuan S, Liu H, Gu M, et al. Characterization of the extrinsic apoptotic pathway in the basal chordate amphioxus[J]. Sci Signal, 2010, 3（139）：ra66.
[11] Lasi M, Pauly B, Schmidt N, et al. The molecular cell death machinery in the simple cnidarian Hydra includes an expanded caspase family and pro-and anti-apoptotic Bcl-2 proteins[J]. Cell Res, 2010, 20（7）：812-825
[12] Boldin MP, Goncharov TM, Goltsev YV, et al. Involvement of MA-CH, a novel MORT1/FADD-interacting protease, in Fas/APO-1-and TNF receptor-induced cell death[J]. Cell, 1996, 85：803-15.
[13] Muzio M, Chinnaiyan AM, Kischkel FC, et al. FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to theCD95（Fas/APO-1）death-inducing signaling complex[J]. Cell, 1996, 85：817-27.
[14] Menze MA, Fortner G, Nag S, et al. Mechanisms of apoptosis in Crustacea：what conditions induce versus suppress cell death?[J]. Apoptosis, 2010, 15（3）：293-312.
[15] Kanda H, Igaki T, Kanuka H, et al. Wengen, a member of the Drosophila tumor necrosis factor receptor superfamily, is required for Eiger signaling[J]. Biol Chem, 2002, 277（32）：28372-28375.
[16] Moreno E, Yan M. Basler K. Evolution of TNF signaling mechani-sms：JNK-dependent apoptosis triggered by Eiger, the Drosophila homolog of the TNF superfamily[J]. Curr Biol, 2002, 12（14）：1263-1268.
[17] Li L, Qiu L, Song L, et al. First molluscan TNFR homologue in Zhikong scallop：molecular characterization and expression analysis[J]. Fish Shellfish Immunol, 2009, 27（5）：625-632.
[18] Su J, Qiu L, Li L, et al. cDNA cloning and characterization of a new member of the tumor necrosis factor receptor family gene from scallop, Chlamys farreri[J]. Mol Biol Rep, 2011, 38（7）：4483-4490.
[19] Yuan S, Yu Y, Huang S, et al. Bbt-TNFR1 and Bbt-TNFR2, two tumor necrosis factor receptors from Chinese amphioxus involve in host defense[J]. Mol Immunol, 2007, 44（5）：756-62.
[20] Rigoulet M, Yoboue ED. Mitochondrial ROS generation and its regulation：mechanisms involved in H2O2 signaling[J]. Antioxid Redox Signal, 2011, 14（3）：459-468.
[21] 孔建强, 赵琦.细胞凋亡机制的研究进展[J].生物技术通报, 2002（3）：15-18.
[22] Imao T, Nagata S. Apaf-1-and Caspase-8-independent apoptosis[J]. Cell Death Differ, 2013, 20：343-352.
[23] Oberst A, Bender C, Green DR. Living with death：the evolution of the mitochondrial pathway of apoptosis in animals[J]. Cell Death Differ, 2008, 15（7）：1139-1146.
[24] Pirger Z, Racz B, Kiss T. Dopamine-induced programmed cell death is associated with cytochrome c release and caspase-3 activation in snail salivary gland cells[J]. Biol Cell, 2009, 101（2）：105-116.
[25] Bayascas JR, Yuste VJ, Benito E, et al. Isolation of AmphiCASP-3/7, an ancestral caspase from amphioxus（Bran-chiostoma floridae）Evolutionary considerations for vertebrate caspases[J]. Cell Death Differ, 2002, 9（10）：1078-1089.
[26] Takada N, Yamaguchi H, Shida K, et al. The cell death machinery controlled by Bax and Bcl-XL is evolutionarily con-served in Ciona intestinalis[J]. Apoptosis, 2005, 10（6）：1211-1220.
[27] Robertson AJ, Croce J, Carbonneau S, et al. The genomic underpinnings of apoptosis in Strongylocentrotus purpuratus[J]. Dev Biol, 2006, 300（1）：321-334.
[28] Robb SM, Ross E, Alvarado A. medGD：the Schmidtea mediterra-nea genome database[J]. Nucleic Acids Res, 2008, 36（Database issue）：D599-D606.
[29] Sullivan JC, Ryan JF, Watson JA, et al. StellaBase：the Nematoste-lla vectensis genomics database[J]. Nucleic Acids Res, 2006, 34（Database issue）：D495-D499.
[30] Wiens M, Krasko A, Perovic S, et al. Caspase-mediated apoptosis in sponges：cloning and function of the phylogenetic oldest apoptotic proteases from Metazoa[J]. Biochim Biophys Acta, 2003, 1593（2-3）：179-189.
[31] Circu ML, Aw TY. Glutathione and apoptosis[J]. Free Radic Res, 2008, 42（8）：689-706.
[32] Kiss T. Apoptosis and its functional significance in molluscs[J]. Apoptosis, 2010, 15（3）：313-321.
[33] Elvitigala DA, Whang I, Premachandra HK, et al. Caspase 3 from rock bream（Oplegnathus fasciatus）：genomic characterization and transcriptional profiling upon bacterial and viral inductions[J]. Fish Shellfish Immunol, 2012, 33（1）：99-110.
[34] Jin P, Hu J, Qian J, et al. Identification and characterization of a putative lipopolysaccharide-induced TNF-α factor（LITAF）gene from Amphioxus（Branchiostoma belcheri）：an insight into the innate immunity of Amphioxus and the evolution of LITAF[J]. Fish Shellfish Immunol, 2012, 32（6）：1223-1228.
[35] Wiens GD, Glenney GW. Origin and evolution of TNF and TNF receptor superfamilies[J]. Dev Comp Immunol, 2011, 35（12）：1324-1335.
[36] Huang WB, Ren HL, Gopalakrishnan S, et al. First molecular cloning of a molluscan caspase from variously colored abalone（Haliotis diversicolor）and gene expression analysis with bacterial challenge[J]. Fish Shellfish Immunol, 2010, 28（4）：587-595.
[37] Lee Y, De Zoysa M, Whang I, et al. Molluscan death effector domain（DED）-containing caspase-8 gene from disk abalone（Haliotis discus discus）：Molecular characterization and expression analysis[J]. Fish Shellfish Immunol, 2011, 30（2）：480-487.
[38] Jin XK, Li WW, He L, et al. Molecular cloning, characterization and expression analysis of two apoptosis genes, caspase and nm23, involved in the antibacterial response in Chinese mitten crab Eriocheir sinensis[J]. Fish Shellfish Immunol, 2011, 30（1）：263-272.
[39] Wang PH, Wan DH, Pang LR, et al. Molecular cloning, characterization and expression analysis of the tumor necrosis factor（TNF）superfamily gene, TNF receptor superfamily gene and lipopolysaccharide-induced TNF- factor（LITAF）gene from Litopenaeus vannamei[J]. Dev Comp Immunol, 2011, 36：39-50.
[40] Romero A, Estévez-Calvar N, Dios S, et al. New insights into the apoptotic process in mollusks：characterization of caspase genes in Mytilus galloprovincialis[J]. PLoS One, 2011, 6（2）：e17003.
[41] Zhi B, Wang L, Wang G, et al. Contribution of the caspase gene sequence diversification to the specifically antiviral defense in invertebrate[J]. PLoS One, 2011, 6（9）：e24955.
[42] Agnello M, Roccheri MC. Apoptosis：focus on sea urchin development[J]. Apoptosis, 2010, 15（3）：322-330.
[43] 王晓梅, 刘保忠, 相建海.文蛤（Meretrix meretrix）幼虫发育过程中细胞凋亡和Caspase功能分析[J].海洋与湖沼, 2009, 40（2）：181-186.
[44] Seipp S, Wittig K, Stiening B, et al. Metamorphosis of Hydractinia echinata（Cnidaria）is caspase-dependent[J]. International Developmental Biology, 2006, 50（1）：63.
[45] Technau U, Miller MA, Bridge D, et al. Arrested apoptosis of nurse cells during Hydra oogenesis and embryogenesis[J]. Dev Biol, 2003, 260：191-206.
[46] Wager RE. The o?genesis and early development of hydra[J]. Biol Bull, 1909, 18（1）：1-36.
[47] Kefaloyianni E, Gourgou E, Ferle V, et al. Acute thermal stress and various heavy metals induce tissue-specific pro-or anti-apoptotic events via the p38-MAPK signal transduction pathway in Mytilus galloprovincialis（Lam.）[J]. J Exp Biol, 2005, 208（23）：4427-4436.
[48] Tomanek L, Zuzow MJ. The proteomic response of the mussel congeners Mytilus galloprovincialis and M. trossulus to acute heat stress：implications for thermal tolerance limits and metabolic costs of thermal stress[J]. J Exp Biol, 2010, 213（20）：3559-3574.
[49] Sun Y, Wang W, Li B, et al. Research articles：synchronized expression of two Bombyx mori caspase family genes, ice-2 and ice-5 in cells induced by ultraviolet irradiation[J]. Int J Indust Entomol, 2008, 17（1）：121-124.
[50] Dunn S. Immunorecognition and immunoreceptors in the Cnidaria[J]. Invertebrate Surviv J, 2009, 6：7-14.
[51] Hatanaka R, Sekine Y. Signaling pathways in invertebrate immune and stress response[J]. Invertebrate Surviv J, 2009, 6：32-43.
[52] Wang M, Yang J, Zhou Z, et al. A primitive Toll-like receptor sig-naling pathway in mollusk Zhikong scallop（Chlamys farreri）[J]. Dev Comp Immunol, 2001, 35（4）：511-520.