植物非经典生长素信号转导通路解析

doi:10.13560/j.cnki.biotech.bull.1985.2020-0523

摘要/Abstract

摘要： 植物激素生长素参与调控植物生长发育的各个过程,包括胚胎发育、器官发生和向性运动等。植物通过协调生长素的合成代谢、极性运输以及信号转导来实现对不同生长发育过程的精准调控。生长素的功能依赖于其信号被感知后经由信号转导通路转换为下游复杂多样的反应。经典的生长素信号转导通路阐明了细胞核内从SCF^TIR1/AFB受体到Aux/IAA蛋白的泛素化降解最终通过ARF转录因子调控基因转录的完整生长素响应过程。该核内信号通路揭示了生长素转录调控生长发育的诸多分子机制,但植物生长发育调控过程中仍有许多生长素响应过程无法通过该经典信号通路解析。重点阐述生长素非经典信号通路的调控机制及其对植物生长发育的重要作用,并讨论和展望生长素非经典信号通路研究目前所面临的挑战以及研究前景。

关键词: Aux/IAAs, 转录调控, 非转录调控, TIR1/AFBs, TMK类受体激酶

Abstract: Phytohormone auxin is involved in various processes of plant growth and development,including embryogenesis,organogenesis,tropism and so on. Plants precisely regulate growth and development by coordinating auxin biosynthesis and metabolism,polar transport and signal transduction. The biological function of auxin relies on the diverse downstream responses converted by signal transduction cascades after being sensed. The canonical auxin signaling pathway starts from its perception by the SCF^TIR1/AFB receptor in nucleus,followed by the ubiquitination-based degradation of Aux/IAA transcription repressors and the release of ARF transcription factors,finally regulates gene transcription. Although this canonical signaling pathway illustrates the molecular mechanisms of auxin in regulating many plant developmental processes,there still have many auxin actions that cannot be explained by this pathway. This review focuses on the regulatory mechanisms of non-canonical auxin signaling pathways and its critical role in plant growth and development,as well as discusses and prospects the challenges and the future research directions in this field.

Key words: Aux/IAAs, transcriptional regulation, non-transcriptional regulation, TIR1/AFBs, TMK receptor-like kinase

马军, 徐通达. 植物非经典生长素信号转导通路解析[J]. 生物技术通报, 2020, 36(7): 15-22.

MA Jun, XU Tong-da. Non-canonical Auxin Signaling Pathway in Plants[J]. Biotechnology Bulletin, 2020, 36(7): 15-22.

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