赭曲霉毒素A的微生物脱毒研究进展

doi:10.13560/j.cnki.biotech.bull.1985.2014.12.003

摘要/Abstract

摘要： 赭曲霉毒素 A(Ochratoxin A，OTA)是一类聚酮化合物，是由曲霉属(Aspergillus spp.)和青霉属(Penicillium spp.)等霉菌产生的次级代谢产物，具有强烈毒性。近年来，国内外已有大量关于 OTA 生物脱毒的研究，主要是 OTA 脱毒功能菌株的筛选，包括细菌、霉菌和酵母菌等。此外，对不同微生物脱毒机理的探索也是研究热点。对上述两方面的研究进展进行归纳和讨论。

关键词: 生物脱毒, 赭曲霉毒素A, 细菌, 真菌, 肠道微生物

Abstract: Ochratoxin A(OTA)is a class of polyketides, which are secondary metabolites produced by Aspergillus spp. and Penicillium spp., having a strong toxicity. In recent years, there are a large number of domestic and international researches on OTA biological detoxification, mainly on screening strains of OTA detoxification, including bacteria, molds and yeasts and so on . In addition, exploring different microbial detoxification mechanism is also a research hotspot. In this paper, these two aspects of progress were summarized and discussed.

Key words: Bio-detoxification, Ochratoxin, A, Bacterial, Fungi, Intestinal microbial

贾欣, 徐诗涵 ,梁志宏, 黄昆仑. 赭曲霉毒素A的微生物脱毒研究进展[J]. 生物技术通报, 2014, 0(12): 18-23.

Jia Xin, Xu Shihan, Liang Zhihong, Huang Kunlun. Bio-detoxification of Ochratoxin A by Microorganism[J]. Biotechnology Bulletin, 2014, 0(12): 18-23.

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