生物技术通报 ›› 2016, Vol. 32 ›› Issue (5): 34-39.doi: 10.13560/j.cnki.biotech.bull.1985.2016.05.005

• 综述与专论 • 上一篇    下一篇

渔用药物防耐药策略研究进展

潘浩12, 王荻1, 卢彤岩1   

  1. 1.中国水产科学研究院黑龙江水产研究所,哈尔滨 150070;
    2.上海海洋大学水产与生命学院,上海 201306
  • 收稿日期:2015-06-30 出版日期:2016-05-25 发布日期:2016-05-27
  • 作者简介:潘浩,男,硕士,研究方向:渔药药理及残留检测技术;E-mail:zcph6666@126.com
  • 基金资助:
    公益性行业(农业)科研专项经费(201203085)

Research Progress on the Strategies of Preventing Drug-resistance in Fishery

PAN Hao12,WANG Di1,LU Tong-yan1   

  1. 1. Heilongjiang River Fisheries Research Institute,Chinese Academy of Fishery Sciences,Harbin 150070;
    2. College of Fisheries and Life Sciences,Shanghai Ocean University,Shanghai 201306
  • Received:2015-06-30 Published:2016-05-25 Online:2016-05-27

摘要: 目前,药物治疗仍然是防治水产动物病害的主要方法,但其不合理应用也诱发了大量耐药细菌的产生。如何制定合理的渔用常用药物防耐药用药策略已成为目前研究的重点。系统的综述了耐药突变选择窗理论、中草药防耐药应用及养殖条件影响在防耐药用药策略方向的研究进展。

关键词: 联合用药, 中草药, 养殖环境, 防耐药策略

Abstract: Currently,the drug treatment is still the main way of preventing and controlling the aquatic animal diseases,but abuse of drugs has also led to a large number of drug-resistant bacteria. How to formulate a reasonable strategies of preventing drug-resistance while applying common drugs in fishery has become the focus on the current study. This paper systematically reviewed the window theory of drug-resistant mutation selection,and the research progress on the strategies of preventing drug-resistance such as applying Chinese herbs and the effects of culture conditions.

Key words: drug combination, Chinese herbs, culture environment, strategies of preventing drug-resistance