Biotechnology Bulletin ›› 2015, Vol. 31 ›› Issue (1): 46-50.doi: 10.13560/j.cnki.biotech.bull.1985.2015.01.007

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Research Progress in Genomic Imprinting in Mammals

Chen Xiuli1,2, Ma Libing   

  1. (1. School of Mathematics Physics and Biological Engineering,Inner Mongolia University of Science and Technology,Baotou 014010;2. Faculty of Biological Science and Technical,Baotou Teachers College,Baotou 014030)
  • Received:2014-07-01 Online:2015-01-09 Published:2015-01-10

Abstract: Genomic imprinting is a genetic phenomenon because of the different parents resulted from the allelic gene expression differences. The causes and the process of genomic imprinting is a hot issue of modern genetics. Mammals many genomic imprinting characteristic makes it become a focus biology problems in the post genome era. The evolution of genomic imprinting has played a special role in mammalian reproduction and development. This paper reviewed the characteristics of genomic imprinting、imprinting mechanism of gene imprinting, gene imprinting and the development of cloned animals, the research progress of the imprinting genes and the disease.

Key words: gene imprinting, mammals, cloned animals, embryonic development