Isolation and Identification of a Deep-sea-derived Fungus FS86 and Its Biological Activities

doi:10.13560/j.cnki.biotech.bull.1985.2016.01.031

Abstract

Abstract: A strain of fungus FS86 was isolated from deep-sea sediment of South China Sea by the spread plate method. According to the culture features, morphological characteristics and ITS sequence analysis, the strain was identified as Cladosporium sphaerospermum. Bioassay results showed that the fermentation extract of the strain FS86 demonstrated significant inhibitory effects against 8 pathogenic fungi and 4 tumor cell lines with MICs of 0.1-4 mg/mL and IC₅₀ values of 0.86-2.13 μg/mL, respectively.

Key words: deep sea fungus, Cladosporium sphaerospermum, isolation, identification, antifungal, cytotoxic

WU Hou-lv, LI Hao-hua, TAN Guo-hui, CHEN Yu-chan, LIU Yun-mei, ZHANG Wei-min. Isolation and Identification of a Deep-sea-derived Fungus FS86 and Its Biological Activities[J]. Biotechnology Bulletin, 2016, 32(1): 195-200.

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