Biotechnology Bulletin ›› 2017, Vol. 33 ›› Issue (7): 35-39.doi: 10.13560/j.cnki.biotech.bull.1985.2017-0194

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Research Advances on Whole Genome Sequencing of Chicken

LI Dong-hua, WANG Xin-lei ,LI Zhuan-jian ,SUN Gui-rong ,KANG Xiang-tao, YAN Feng-bin   

  1. College of Animal Science and Veterinary Medicine,Henan Agricultural University,Henan Innovative Engineering Research Center of Poultry Germplasm Resource,Zhengzhou 450002
  • Received:2017-03-14 Online:2017-07-11 Published:2017-07-11

Abstract: Chicken possesses unique biological traits. Whole genome sequencing is the sequencing of all genes in a biological genome,mainly including de novo sequencing and whole genome re-sequencing. With the rapid development of sequencing technology in recent years,there have been great progresses in chicken genome research,which plays a critical role in explaining the biological characteristics of chicken and shortening the period of molecular breeding. This paper mainly describes the de novo sequencing completion of whole genome in different chicken cultivars,as well as the wide application of whole genome re-sequencing technology in analyzing genetic diversity,revealing evolutionary mechanisms and genetic mechanisms of quality traits,and further discusses the existing issues and potential prospects in the chicken whole genome sequencing. The aim is to provide a resource for genetic improvement and breeding programs.

Key words: chicken, genome, sequencing