Biotechnology Bulletin ›› 2017, Vol. 33 ›› Issue (9): 32-47.doi: 10.13560/j.cnki.biotech.bull.1985.2017-0401

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Research Progress on Red Fluorescent Protein

WANG Fei,YANG Hai-tao,WANG Ze-fang   

  1. School of Life Science,Tianjin University,Tianjin 300000
  • Received:2017-05-25 Online:2017-09-01 Published:2017-09-15

Abstract: Since the first discovery of fluorescent proteins,its ever-increasing fluorescence spectra and the increasing number of photochemical properties have led to an increasing position in biological research. The red fluorescent protein emerged in 1999 dominated the biology study with its superiority. This paper focuses on the growing importance of fluorescent protein discovery from now on,as well as the significant advantages of red fluorescent protein. In addition,we discuss the characteristics of several common red fluorescent proteins and their advantages and disadvantages in biology research,providing an alternative for the future research of red fluorescent protein.

Key words: red fluorescent protein, far-red fluorescent protein, fluorescent timers, LSSFP, PAFP