Research Progress on the Development and Application of Dextranase

doi:10.13560/j.cnki.biotech.bull.1985.2018-1021

Abstract

Abstract: Dextranase is a kind of enzyme that can specifically catalyzes the hydrolysis of α-1,6-glucosidic bonds on dextran. Dextran,the substrate of dextranase,is a glucan produced by the fermentation of sucrose via some microorganisms. Dextran is widely used in medicine,food,materials and other fields,but it brings the adverse effects on oral health,sugar production,etc. Studies on dextran,dextran hydrolysates and other polysaccharides are getting increasingly advanced and dextranase plays an increasingly important role;but the overall development level of dextranase preparation is still not high and its application is still limited. This review summarizes the development and researches on the construction of dextranase-producing strains,fermentation and purification of dextranase,dextranase immobilization,characterization of enzymatic properties,enzyme activity enhancement,etc.,as well as the research progresses on applying dextranase in sugar production,food,medicine and materials,including the research results in our team. Then the paper discusses the issues in the development and application and prospects the future research and development directions.

Key words: dextranase, dextran, biofilm, sugar manufacturing, plasma substitute

CHANG Guo-wei, HUANG Zeng-wei, LI Zhi-de, LIANG Da-feng. Research Progress on the Development and Application of Dextranase[J]. Biotechnology Bulletin, 2019, 35(6): 196-204.

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