Research Progress in Chemical Constituents of Taiwanofungus camphoratum and Its Pharmacological Activities

doi:10.13560/j.cnki.biotech.bull.1985.2021-1052

Abstract

Abstract:

In recent years,Taiwanofungus camphoratum has been widely concerned for its rare resources and unique pharmacological efficacy. It contains a lot of triterpenoids,polysaccharides and other functional components in T. camphoratum fruiting body,mycelium and fermentation broth,and there are published reports on some of chemical constituents have many pharmacological effects such as anti-cancer,anti-oxidant,anti-inflammatory and so on. This paper comprehensively sorted the publicly reported main compounds,biological and chemical synthesis and their pharmacological effects,and proposed the expectations and indicated the direction for the development of T. camphoratum industry,aiming to provide a scientific references for the study,development,and application of T. camphoratum,to increase the commercialization and market value of T. camphoratum and to enhance the development of T. camphoratum in China and all over the world.

Key words: Taiwanofungus camphoratum, triterpenoids, polysaccharide, synthesis, pharmacological activities

LI Jing, FENG Na, WANG Sheng-yang, LIN Zhan-xi. Research Progress in Chemical Constituents of Taiwanofungus camphoratum and Its Pharmacological Activities[J]. Biotechnology Bulletin, 2021, 37(11): 14-31.

Figures/Tables 9

References 114

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序号No.	名称Name	序号No.	名称Name
1	Methyl antcinate A^[12]	23	Antcamphin K^[20]
2	Methyl antcinate G^[13]	24	Antcamphin L^[20]
3	Methyl antcinate H^[13]	25	15-acetyldehydrosulfurenic^[19]
4	Methyl antcinate L^[14]	26	15α-acetyl-dehydrosulphurenic acid^[16]
5	Zhankuic acid B^[15]	27	Antcamphin E^[20]
6	Zhankuic acid D^[16]	28	Antcamphin F^[20]
7	Antcin A^[17]	29	Antcamphin G^[20]
8	Antcin B （Zhankuic acid A）^[15,17,23]	30	Methyl antcinateK^[14]
9	Antcin C^[17,18]	31	Antcamphin H^[20]
10	Antcin D （Zhankuic acid F）^[17,18]	32	Antcin K^[18]
11	Antcin E^[13]	33	Dehydrosulphurenic acid^[16]
12	Antcin F^[13]	34	Dehydroeburicoic acid^{[16, 19]}
13	Antcin G^[19]	35	15-O-acetylganolucidate A^[21]
14	Antcin H （Zhankuic acid C）^[15,18]	36	Ethyl lucidenate A^[21]
15	Antcin M^[14]	37	Ethyl lucidenate F^[21]
16	Zhankuic acid E^[16]	38	3, 7, 11-trioxolanosta-8, 24-dien-26-al, 26-carboxylic acid, 11a-alcohol, me ester^[22]
17	Antcamphin A^[20]	39	3, 7, 11-trioxolanosta-8, 24-dien-26-oic acid^[22]
18	Antcamphin B^[20]	40	3, 7, 12-trihydroxy-11, 15, 23-trioxolanost-8-en-26-oic acid, 3, 7, 12-triketone, me ester^[22]
19	Antcamphin C^[20]	41	3, 7, 12-trihydroxy-11, 15, 23-trioxolanost-8-en-26-oic acid, 3, 7, 12-triketone, et ester^[22]
20	Antcamphin D^[20]	42	Eburicol^[23]
21	Antcamphin I^[20]	43	Dehydroeburicoic acid monoucetate^[16]
22	Antcamphin J^[20]	44	Epi-friedelinol^[24]

序号No.	名称Name	序号No.	名称Name
1	Methyl antcinate A^[12]	23	Antcamphin K^[20]
2	Methyl antcinate G^[13]	24	Antcamphin L^[20]
3	Methyl antcinate H^[13]	25	15-acetyldehydrosulfurenic^[19]
4	Methyl antcinate L^[14]	26	15α-acetyl-dehydrosulphurenic acid^[16]
5	Zhankuic acid B^[15]	27	Antcamphin E^[20]
6	Zhankuic acid D^[16]	28	Antcamphin F^[20]
7	Antcin A^[17]	29	Antcamphin G^[20]
8	Antcin B （Zhankuic acid A）^[15,17,23]	30	Methyl antcinateK^[14]
9	Antcin C^[17,18]	31	Antcamphin H^[20]
10	Antcin D （Zhankuic acid F）^[17,18]	32	Antcin K^[18]
11	Antcin E^[13]	33	Dehydrosulphurenic acid^[16]
12	Antcin F^[13]	34	Dehydroeburicoic acid^{[16, 19]}
13	Antcin G^[19]	35	15-O-acetylganolucidate A^[21]
14	Antcin H （Zhankuic acid C）^[15,18]	36	Ethyl lucidenate A^[21]
15	Antcin M^[14]	37	Ethyl lucidenate F^[21]
16	Zhankuic acid E^[16]	38	3, 7, 11-trioxolanosta-8, 24-dien-26-al, 26-carboxylic acid, 11a-alcohol, me ester^[22]
17	Antcamphin A^[20]	39	3, 7, 11-trioxolanosta-8, 24-dien-26-oic acid^[22]
18	Antcamphin B^[20]	40	3, 7, 12-trihydroxy-11, 15, 23-trioxolanost-8-en-26-oic acid, 3, 7, 12-triketone, me ester^[22]
19	Antcamphin C^[20]	41	3, 7, 12-trihydroxy-11, 15, 23-trioxolanost-8-en-26-oic acid, 3, 7, 12-triketone, et ester^[22]
20	Antcamphin D^[20]	42	Eburicol^[23]
21	Antcamphin I^[20]	43	Dehydroeburicoic acid monoucetate^[16]
22	Antcamphin J^[20]	44	Epi-friedelinol^[24]

序号No.	名称Name	序号No.	名称Name
45	1, 6-cyclo-1, 10-secoergosta-5, 7, 9, 22-tetraen-3-ol^[27]	50	Stigmasterol^[24]
46	Ergostatrien-3β-ol^[28,29]	51	β-sitostenone^[24]
47	Ergosta-4, 6, 8(14), 22-tetraen-3-one^[24]	52	β-sitosterol^[23]
48	Ergosterol peroxide^[29,30]	53	(14α, 22E)-14-hydroxyergosta-7, 22-diene-3, 6-dione^[22]

序号No.	名称Name	序号No.	名称Name
45	1, 6-cyclo-1, 10-secoergosta-5, 7, 9, 22-tetraen-3-ol^[27]	50	Stigmasterol^[24]
46	Ergostatrien-3β-ol^[28,29]	51	β-sitostenone^[24]
47	Ergosta-4, 6, 8(14), 22-tetraen-3-one^[24]	52	β-sitosterol^[23]
48	Ergosterol peroxide^[29,30]	53	(14α, 22E)-14-hydroxyergosta-7, 22-diene-3, 6-dione^[22]

序号No.	名称Name	序号No.	名称Name
54	14-dexyandrographolide^[31]	73	19-hydroxy-8(17)-labden-16, 15-olide^[31]
55	3, 19-dihydroxy-8(17), 11-labdadien-16, 15-olide^[31]	74	Pinusolidic acid^[31]
56	3, 19-dihydroxy-8(17), 11-labdadien-16, 15-olide, 13-epimer^[31]	75	2, 3-dimethoxy-5-methyl-1, 4-benzoquinone^[38]
57	14-deoxy-11, 12-didehyd-roandrographolide^[31]	76	2, 3, 6-trimethoxy-4-methylphenol^[38]
58	Antrocin^[32]	77	2, 3, 6-trimethoxy-5-methylphenol^[37]
59	Antrocamphin A^{[19, 24]}	78	6-methoxy-4-methyl-7-(1-methylethenyl)-1, 3-benzodioxol-5-ol^[37]
60	Antrocamphin B^[24]	79	2-hydroxy-4, 4’-dimethoxy-3, 5'-dimethyl-2’, 3':5, 6-bis(methylenedioxy)biphenyl^[37]
61	Antrocamphin C^[19]	80	4, 4’-dihydroxy-5, 5'-dimethoxy-6, 6’-dimethyl-2, 3:2’, 3'-bis(methylenedioxy)biphenyl^[37]
62	Antrocamphin O^[33]	81	2-hydroxybenzeneethanol^[29]
63	Antrodioxolanone^[24]	82	4, 5-dimethoxy-2, 3-(methylenedioxy)benzoic acid^[39]
64	2-(4-hydroxyphenyl)-3-(2-methylpropyl)-2-butenedioic acid, di-me ester^[34]	83	4-isobutylphenol^[35]
65	2, 3-dimethoxy-5-methyl-1, 4-benzoquinone^[35]	84	5-methyl-1, 3-benzodioxole-4, 7-dione^[35]
66	2, 3, 4, 5-tetrahydroxybenzoic acid^[24]	85	5-methoxy-7-methyl-1, 3-benzodioxol-4-ol^[40]
67	2, 3-dimethoxy-5-methyl-1, 4-benzenediol^[35]	86	5-methyl-1, 3-benzodioxole-4, 7-diol^{[35, 40-41]}
68	4, 7-dimethoxy-5-methyl-1, 3-benzodioxole^{[19, 32]}	87	7-methoxy-6-methyl-1, 3-benzodioxol-4-ol^{[37, 40]}
69	2, 4-dimethoxy-6-methyl-1, 3-benzenediol^[36]	88	2-methoxy-6-methyl-1, 4-benzoquinone^[35]
70	4, 4’, 7, 7’-tetramethoxy-6, 6’-dimethyl-5, 5'-bi-1, 3-benzodioxole^{[32, 37]}	89	4-hydroxysesamin^[23]
71	(-)-sesamin^[23]	90	2-(2-hydroxyethyl)phenol^[29]
72	(+)-sesamin^[23]	91	3, 19-dihydroxy-8(17), 11-labdadien-16, 15-olide, 13-Epimer^[33]