Biotechnology Bulletin ›› 2012, Vol. 0 ›› Issue (12): 150-155.

• Study Report • Previous Articles     Next Articles

Screening and Identification of a Rare Actinomycetes ExhibitingIMPDH Inhibitive Activity

Yuan Lijie1,2, Liu Aihua1, Zhang Yuqin 2, Yu Liyan2, Wang Qian1, Zhang Yueqin2   

  1. 1 Hebei United University Medical College,Tangshan 063000 ;2 Institute of Medicinal Biotechnology,Chinese Academy of Medical Sciencesand Peking Union Medical College,Beijing 100050
  • Received:2012-06-04 Revised:2013-01-25 Online:2012-12-26 Published:2013-02-06

Abstract: One actinomycete strain I06-03147 was isolated from rhizosphere soil of medicinal plant Aconitum carmichaeli Debx. collectedfrom Chongqing. The fermentation broth of strain I06-03147 exhibited inhibitive activity of IMPDH. In view of morphology, physiological andbiochemical characteristics, chemotaxonomic data, phylegentic analysis based on 16S rRNA gene sequence, the studied strain belonged to genusKineosporia.