Abstract: Sugar is not only metabolite, but also as a signal molecule to regulate metabolic process to adopt diverse environments. Among the sugar, trehalose-6-phosphate（T6P）is one of signal molecules highlighted. Based on recently progress of study on T6P through molecular biological approach, This review discussed pathways of metabolism regulation of T6P as a molecular signal involving in, including diurnal cycle and phytohormone as well as response of enviroment stress. Function, behavior, questions remaining to answer and methods of study relevant to T6P as a molecular signal were evaluated in the pathways.

Key words: Trehalose-6-phosphate, Molecular signal, Stress response, Diurnal cycle, Phytohormones