Biotechnology Bulletin ›› 2013, Vol. 0 ›› Issue (10): 40-45.

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SarA Family Proteins and Its Post-Translational Modification in Staphylococcus aureus

Wu Ruirui, Zhu Fuxing   

  1. (College of Plant Science & Technology of Huazhong Agricultural University,Wuhan 430070)
  • Received:2013-03-25 Revised:2013-10-15 Online:2013-10-14 Published:2013-10-15

Abstract: A class of family proteins found in staphylococcus aureus genome is similar to SarA, it contributes to the main physiological and virulence of staphylococcus aureus. protein cysteine phosphorylation of MgA/SarA/SarZ family or Oxidation and reduction modification can caused the change of protein conformation, which regulates the virulence factor of S. aureus and to vancomycin-resistant. SarA family proteins are homologous and interacted, and its post-translational modification is similar.

Key words: Family proteins of SarA, Phosphorylation, Oxidation and reduction modification, MgrA, SarZ