Effects of PFOS on the Activities of Antioxidant Enzyme in Regenerated Dugesia japonica

doi:10.13560/j.cnki.biotech.bull.1985.2015.10.032

Abstract

Abstract: Perfluorooctane sulfonate（PFOS）, a persistent organic pollutant, has been a typical predominant perfluorinated chemicals（PFCs）in the environment. In this study, we used regenerated planarians（Dugesia japonica）to evaluate the toxicological effects of PFOS on the activities of antioxidant enzyme. The results indicated that PFOS stimulated planarians to generate the stress responses. In the early stage of regeneration, PFOS stress caused oxidative damage and lipid peroxide of planarians, with the concentration of PFOS increasing, oxidative damage degree of planarian intensified; at the 5th day of regeneration, the body produced oxidation reaction to eliminate oxygen free radicals; in the late stage of regeneration, the oxidation reaction of planarian was no longer significant because of drug tolerance.

Key words: PFOS, Dugesia japonica, regeneration, antioxidant enzyme activity

Miao Zili, Yuan Zuoqing. Effects of PFOS on the Activities of Antioxidant Enzyme in Regenerated Dugesia japonica[J]. Biotechnology Bulletin, 2015, 31(10): 211-215.

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