Research Progress in the Involvement of Intracellular Transport Regulated by Endogenous Elicitors in Plant Growth and Development and Response to Adverse Stress

doi:10.13560/j.cnki.biotech.bull.1985.2025-0124

Abstract

Abstract:

Endogenous elicitors are endogenous signal molecules released by plants in response to pathogen infection or mechanical damage. When plants perceive the threat of infection by pathogens or suffer mechanical damage, they release endogenous elicitors. Once produced, these elicitors can be recognized by pattern recognition receptors (PRRs) located on the plasma membrane of the cell, triggering and amplifying an immune response (such as PTI). Endogenous elicitors can regulate the endocytosis of PRRs protein by means of protein modifications such as phosphorylation and ubiquitination, and regulate the intracellular cycle or degradation of PRRs, thus affecting the transmission of immune signals. These processes are not only involved in plant defense against pathogens, but also related to plant growth and development and regulation of resistance response.In this paper, the latest research progress of endogenous elicitors and their receptors is reviewed comprehensively and systematically. The regulation of endogenous elicitors on PRRs intracellular transport is discussed in detail, and the key role of endogenous elicitors in plant growth and development and resistance is also analyzed in depth, aiming to provide a new perspective for understanding the molecular and cytological mechanism of plant resistance response.

Key words: plant endogenous elicitors, pattern recognition receptors (PRRs), intracellular transport, plant immunity

LI Si-bo, QIAN Hong-ping, XU Chang-wen, WANG Xiao, LIN Jin-xing, CUI Ya-ning. Research Progress in the Involvement of Intracellular Transport Regulated by Endogenous Elicitors in Plant Growth and Development and Response to Adverse Stress[J]. Biotechnology Bulletin, 2025, 41(7): 17-27.

Figures/Tables 2

Fig. 1 Pep1 secretion and PEPR1 endocytosisExtracellular Ca2+ quickly flows into the cell when plants are subjected to specific stimuli, which in turn causes the concentration of intracellular Ca2+ to rise rapidly, activates cysteine protease MC4, thus cutting the specific site of the C terminal of AtPROPEP1 and releasing AtPep1 into the cytoplasm. Finally, AtPep1 may be secreted extracellular by MVB fusion with plasma membrane. Extracellular AtPep1 can recognize and bind to the PEPR1 receptor on the plasma membrane, induce heterodimerization of PEPR1 and co-receptor BAK1, induce endocytosis of PEPR1, and regulate immune signal transmission. The AtPep 1-PEPR1 complex may bypass TGN/EE and internalize directly to MVB. MC4: Ca2+-dependent metacaspase 4; MVB: multivesicular body; PROPEP 1: precursor of Pep 1; Pep 1: plant elicitor peptide 1; PEPR1: Pep 1 receptor; BAK1: brassinosteroid-insensitive 1-associated receptor kinase 1

Table 1 Biological effects of endogenous elicitors and pattern recognition receptors

配体 Ligand	受体 Receptor	生物学效应 Biological effects
AtPep1	PEPR1	激活MAPK级联反应，促进防御相关基因的转录迅速诱导细胞内活性氧（如超氧阴离子、过氧化氢）的产生调控植物叶片免疫和主根生长抑制
SYS	SYR1	激活蛋白酶抑制剂基因的表达，抑制昆虫和食草动物的消化蛋白酶 MAPK磷酸化、钙调素基因表达的上调调节植物激素的平衡来影响植物的生长速度和形态
RALF1	FER	抑制质子泵（H⁺-ATPase）的活性，引起细胞生长和扩张的减缓影响细胞形态和细胞壁的合成
PIP1	RLK7	对PAMP flg22信号起放大作用诱导SA信号而非JA信号参与植物免疫调节

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