Research Advances in the Mechanism and Signal Transduction of Plant Disease Resistance

doi:10.13560/j.cnki.biotech.bull.1985.2016.10.013

Abstract

Abstract: The mechanism of plant disease resistance is the focus of plant pathology. With the development of the molecular biology,people has gained more and more insights into the interaction between plant host and pathogens. In this review,the recent research advances on molecular mechanism of plants disease resistance are summarized. It also presented the function of several signal molecular such as calcium Ion,nitric oxide,reactive oxygen species,salicylic acid,jasmonic acid/ethylene,and heterotrimeric G proteins,which are known to play important role in inducing plant defense response. In addition,the prospect of future work on plant defense research is discussed in the review, aiming to offer new thinking for the development of disease control stratey.

Key words: mechanism of plant disease resistance, signal molecular, defense response, signal transduction

DING Li-na, YANG Guo-xing. Research Advances in the Mechanism and Signal Transduction of Plant Disease Resistance[J]. Biotechnology Bulletin, 2016, 32(10): 109-117.

References

[1] Chisholm ST, Coaker G, Day B, et al. Host-microbe interactions：shaping the evolution of the plant immune response[J]. Cell, 2006, 124（4）：803-814.
[2] Jones JD, Dangl JL. The plant immune system[J]. Nature, 2006, 444（7117）：323-329.
[3] Grant M, Lamb C. Systemic immunity[J]. Current Opinion in Plant Biology, 2006, 9（4）：414-420.
[4] Lee S, Rojas CM, Ishiga Y, et al. Arabidopsis heterotrimeric G-proteins play a critical role in host and nonhost resistance against Pseudomonas syringae pathogens[J]. PLoS One, 2013, 8（12）：e82445.
[5] Bundó M, Coca M. Enhancing blast disease resistance by overexpression of the calcium-dependent protein kinase OsCPK4 in rice[J]. Plant Biotechnology Journal, 2015, doi:10. 1111/pbi. 12500.
[6] Martos GG, Terán Mdel M, Díaz Ricci JC. The defence elicitor AsES causes a rapid and transient membrane depolarization, a triphasic oxidative burst and the accumulation of nitric oxide[J]. Plant Physiology Biochemistry, 2015, 97：443-450.
[7] Zhang Y, Li D, Zhang H, et al. Tomato histone H2B monoubiquitin-ation enzymes SlHUB1 and SlHUB2 contribute to disease resistance against Botrytis cinerea through modulating the balance between SA- and JA/ET-mediated signaling pathways[J]. BMC Plant Biology, 2015, 15：252.
[8] 覃瀚仪, 李魏, 戴良英. 植物代谢产物在抗病反应中的功能研究进展[J]. 中国农学通报, 2015, 31（18）：256-259.
[9] 宗兆锋, 康振生. 植物病理学原理[M]. 北京：中国农业出版社, 2002：226-230.
[10] Vaz Patto MC, Rubiales D. Unveiling common responses of Medicago truncatula to appropriate and inappropriate rust species[J]. Frontiers in Plant Science, 2014, 5：618.
[11] Keerthisinghe S, Nadeau JA, Lucas JR, et al. The Arabidopsis leucine-rich repeat receptor-like kinase MUSTACHES enforces stomatal bilateral symmetry in Arabidopsis[J]. Plant Journal, 2015, 81（5）：684-694.
[12] Abou-Attia MA, Wang X, Nashaat Al-Attala M, et al. TaMDAR6 acts as a negative regulator of plant cell death and participates indirectly in stomatal regulation during the wheat stripe rust-fungus interaction[J]. Physiologia Plantarum, 2016, 156（3）：262-277.
[13] Shafiei R, Hang C, Kang JG, et al. Identification of loci controlling non-host disease resistance in Arabidopsis against the leaf rust pathogen Puccinia triticina[J]. Molecular Plant Pathology, 2007, 8（6）：773-784.
[14] Suh SJ, Wang YF, Frelet A, et al. The ATP binding cassette transporter AtMRP5 modulates anion and calcium channel activities in Arabidopsis guard cells[J]. Journal of Biological Chemistry, 2007, 282（3）：1916-1924.
[15] Vargas P, Farias GA, Nogales J, et al. Plant flavonoids target Pseudomonas syringae pv. tomato DC3000 flagella and type III secretion system[J]. Environmental Microbiology Reports, 2013, 5（6）：841-850.
[16] Han Y, Zhang K, Yang J, et al. Differential expression profiling of the early response to Ustilaginoidea virens between false smut resistant and susceptible rice varieties[J]. BMC Genomics. 2015, 16（1）：955.
[17] Ding L, Xu H, Yi H, et al. Resistance to hemi-biotrophic F. graminearum infection is associated with coordinated and ordered expression of diverse defense signaling pathways[J]. PLoS One, 2011, 6：e19008.
[18] Cho MH, Lee SW. Phenolic phytoalexins in rice：biological functions and biosynthesis[J]. International Journal of Molecular Sciences, 2015, 16（12）：29120-29133.
[19] Yamamura C, Mizutani E, Okada K, et al. Diterpenoid phytoalexin factor, a bHLH transcription factor, plays a central role in the biosynthesis of diterpenoid phytoalexins in rice[J]. Plant Journal, 2015,;84（6）：1100-1113.
[20] Schmelz EA, Kaplan F, Huffaker A, et al. Identity, regulation, and activity of inducible diterpenoid phytoalexins in maize[J]. Proceedings of the National Academy of Sciences of the United States of America. 2011, 108（13）：5455-4560.
[21] de Wit PJ. How plants recognize pathogens and defend themselves[J]. Cellular and Molecular Life Sciences, 2007, 64（21）：2726-2732.
[22] Stam R, Mantelin S, McLellan H, et al. The role of effectors in nonhost resistance to filamentous plant pathogens[J]. Frontiers in Plant Science, 2014, 5：582.
[23] Schoonbeek HJ, Wang HH, Stefanato FL, et al. Arabidopsis EF-Tu receptor enhances bacterial disease resistance in transgenic wheat[J]. New Phytologist, 2015, 206（2）：606-613.
[24] Kumar D, Kirti PB. Pathogen-induced SGT1 of Arachis diogoi induces cell death and enhanced disease resistance in tobacco and peanut[J]. Plant Biotechnology Journal, 2015, 13（1）：73-84.
[25] Bentur JS, Rawat N, Divya D, et al. Rice-gall midge interactions：Battle for survival[J]. Journal of Insect Physiology, 2015, pii：S0022-1910（15）00198-5.
[26] Durrant WE, Dong X. Systemic acquired resistance[J]. Annual Review of Phytopathology, 2004, 42：185-209.
[27] Lee HJ, Park YJ, Seo PJ, et al. Systemic immunity requires SnRK2. 8-mediated nuclear import of NPR1 in Arabidopsis[J]. Plant Cell, 2015, 27（12）：3425-3438.
[28] Jaouannet M, Rodriguez PA, Thorpe P, et al. Plant immunity in plant-aphid interactions[J]. Frontiers in Plant Science, 2014, 5：663.
[29] Strugala R, Delventhal R, Schaffrath U. An organ-specific view on non-host resistance[J]. Frontiers in Plant Science, 2015, 6：526.
[30] Kang Z, Buchenauer H. Immunocytochemical localization of cell wall-bound thionins and hydroxyproline-rich glycoproteins in Fusarium culmorum-infected wheat spikes[J]. Journal of Phytopathology, 2003, 151（3）：120-129.
[31] Oh SK, Lee S, Chung E, et al. Insight into types I and II nonhost resistance using expression patterns of defense-related genes in tobacco[J]. Planta, 2006, 223（5）：1101-1107.
[32] Hückelhoven R. Powdery mildew susceptibility and biotrophic infection strategies[J]. FEMS Microbiology Letters, 2005, 245（1）：9-17.
[33] Ellis J. Insights into nonhost disease resistance：can they assist disease control in agriculture?[J]Plant Cell, 2006, 18（3）：523-528.
[34] Douchkov D, Lück S, Johrde A, et al. Discovery of genes affecting resistance of barley to adapted and non-adapted Powdery mildew fungi[J]. Genome Biology, 2014, 15（12）：518.
[35] Hiruma K, Takano Y. Roles of EDR1 in non-host resistance of Arabidopsis[J]. Plant Signaling & Behavior, 2011, 6（11）：1831-1833.
[36] Johansson ON, Fantozzi E, Fahlberg P, et al. Role of the penetration-resistance genes PEN1, PEN2 and PEN3 in the hypersensitive response and race-specific resistance in Arabidopsis thaliana[J]. Plant Journal, 2014, 79（3）：466-476.
[37] Lipka U, Fuchs R, Lipka V. Arabidopsis non-host resistance to Powdery mildews[J]. Current Opinion in Plant Biology, 2008, 11（4）：404-411.
[38] Wen Y, Wang W, Feng J, et al. Identification and utilization of a sow thistle Powdery mildew as a poorly adapted pathogen to dissect post-invasion non-host resistance mechanisms in Arabidopsis[J]. Journal of Experimental Botany, 2011, 62（6）：2117-2129.
[39] Tuteja N, Mahajan S. Calcium signaling network in plants[J]. Plant Signaling & Behavior, 2007, 2（2）：79-85.
[40] Arnaud D, Hwang I. A sophisticated network of signaling pathways regulates stomatal defenses to bacterial pathogens[J]. Molecular Plant, 2015, 8（4）：566-581.
[41] Urquhart W, Gunawardena AH, Moeder W, et al. The chimeric cyclic nucleotide-gated ion channel ATCNGC11/12 constitutively induces programmed cell death in a Ca 2+ dependent manner[J]. Plant Molecular Biology, 2007, 65（6）：747-761.
[42] Beneloujaephajri E, Costa A, L'Haridon F, et al. 2013. Production of reactive oxygen species and wound-induced resistance in Arabidopsis thaliana against Botrytis cinerea are preceded and depend on a burst of calcium[J]. BMC Plant Biology 13：160.
[43] Ali R, Ma W, Lemtiri-Chlieh F, et al. Death don’t have no mercy and neither does calcium：Arabidopsis CYCLIC NUCLEOTIDE GATED CHANNEL2 and innate immunity[J]. Plant Cell, 2007, 19（3）：1081-1095.
[44] Jeandroz S, Lamotte O, Astier J, et al. There's more to the picture than meets the eye：nitric oxide cross talk with Ca 2+ signaling[J]. Plant Physiology, 2013, 163：459-470.
[45] Du L, Ali GS, Simons KA, et al. Ca 2+ /calmodulin regulates salicylic-acid-mediated plant immunity[J]. Nature, 2009, 457（7233）：1154-1158.
[46] Zhang L, Du L, Shen C, et al. Regulation of plant immunity through ubiquitin-mediated modulation of Ca 2+ -calmodulin-AtSR1/CAMTA3 signaling[J]. Plant Journal, 2014, 78（2）：269-281.
[47] Liu D, Wen J, Liu J, et al. The roles of free radicals in amyotrophic lateral sclerosis：reactive oxygen species and elevated oxidation of protein, DNA, and membrane phospholipids[J]. FASEB Journal, 1999, 13（15）：2318-2328.
[48] Ishibashi Y, Kasa S, Sakamoto M, et al. A role for reactive oxygen species produced by NADPH oxidases in the embryo and aleurone cells in barley seed germination[J]. PLoS One, 2015, 10（11）：e0143173.
[49] You J, Chan Z. ROS regulation during abiotic stress responses in crop plants[J]. Frontiers in Plant Science, 2015, 6：1092.
[50] Slesak I, Libik M, Karpinska B, et al. The role of hydrogen peroxide in regulation of plant metabolism and cellular signaling in response to environmental stresses[J]. Acta Biochimica Polonica, 2007, 54（1）：39-45.
[51] Ryals JA, Neuenschwander UH, Willits MG, et al. Systemic acquired resistance[J]. Plant Cell, 1996, 8：1809-1819.
[52] Park SW, Kaimoyo E, Kumar D, et al. Methyl salicylate is a critical mobile signal for plant systemic acquired resistance[J]. Science, 2007, 318（5847）：113-116.
[53] Chakravortty D, Kato Y, Sugiyama T, et al. The inhibitory action of sodium arsenite on lipopolysaccharide-induced nitric oxide production in RAW 267. 4 macrophage cells：a role of Raf-1 in lipopolysaccharide signaling[J]. Journal of Immunology, 2001, 166（3）：2011-2017.
[54] Massoud K, Barchietto T, Le Rudulier T, et al. Dissecting phosphite-induced priming in Arabidopsis infected with Hyaloperonospora arabidopsidis[J]. Plant Physiology, 2012, 159（1）：286-298.
[55] Spoel SH, Mou Z, Tada Y, et al. Proteasome-mediated turnover of the transcription coactivator NPR1 plays dual roles in regulating plant immunity[J]. Cell, 2009, 137（5）：860-872.
[56] Zhang X, Chen S, Mou Z. Nuclear localization of NPR1 is required for regulation of salicylate tolerance, isochorismate synthase 1 expression and salicylate accumulation in Arabidopsis[J]. Journal of Plant Physiology, 2009, 167（2）：144-148.
[57] Desveaux D, Maréchal A, Brisson N. Whirly transcription factors：defense gene regulation and beyond[J]. Trends in Plant Science, 2005, 10：95-102.
[58] Shah J, Kachroo P, Klessig DF. The Arabidopsis ssi1 mutation restores pathogenesis-related gene expression in npr1 plants and renders defensin gene expression salicylic acid dependent[J]. Plant Cell, 1999, 11（2）：191-206.
[59] Yang YX, Ahammed GJ, Wu C, et al. Crosstalk among jasmonate, salicylate and ethylene signaling pathways in plant disease and immune responses[J]. Current Protein and Peptide Science, 2015, 16（5）：450-461.
[60] Pozo MJ, Van Der Ent S, Van Loon LC, et al. Transcription factor MYC2 is involved in priming for enhanced defense during rhizobacteria-induced systemic resistance in Arabidopsis thaliana[J]. New Phytologist, 2008, 180（2）：511-523.
[61] Gaudet DA, Wang Y, Penniket C, et al. Morphological and molecular analyses of host and nonhost interactions involving barley and wheat and the covered smut pathogen Ustilago hordei[J]. Molecular Plant-Microbe Interactions, 2010, 23（12）：1619-1634.
[62] Yan L, Zhai Q, Wei J, et al. Role of tomato lipoxygenase D in wound-induced jasmonate biosynthesis and plant immunity to insect herbivores[J]. PLoS Genetics, 2013, 9（12）：e1003964.
[63] Lorenzo O, Piqueras R, Sáanchez-Serrano JJ, et al. ETHYLENE RESPONSE FACTOR1 integrates signals from ethylene and jasmonate pathways in plant defense[J]. Plant Cell, 2003, 15（1）：165-178.
[64] Lorenzo O, Chico JM, Sáanchez-Serrano JJ, et al. JASMONATE-INSENSITIVE1 encodes a MYC transcription factor essential to discriminate between different jasmonate regulated defense responses in Arabidopsis[J]. Plant Cell, 2004, 16（7）：1938-1950.
[65] Zarate SI, Kempema LA, Walling LL, et al. Silverleaf whitefly induces salicylic acid defenses and suppresses effectual jasmonic acid defenses[J]. Plant Physiology, 2007 143（2）：866-875.
[66] Penninckx IA, Thomma BP, Buchala A, et al. Concomitant activation of jasmonate and ethylene response pathways is required for induction of a plant defensin gene in Arabidopsis[J]. Plant Cell, 1998, 10（12）：2103-2113.
[67] Modolo LV, Cunha FQ, Braga MR, et al. Nitric oxide synthase-mediated phytoalexin accumulation in soybean cotyledons in response to the Diaporthe phaseolorum f. sp. meridionalis elicitor[J]. Plant Physiology, 2002, 130（3）：1288-1297.
[68] Stefano MD, Ferrarini A, Delledonne M. Nitric oxide functions in the plant hypersensitive disease resistance response[J]. BMC Plant Biology, 2005, 5（Suppl 1）：S10.
[69] Asai S, Ohta K, Yoshioka H. MAPK signaling regulates nitric oxide and NADPH oxidase-dependent oxidative bursts in Nicotiana benthamiana[J]. Plant Cell, 2008, 20（5）：1390-1406.
[70] Asai S, Mase K, Yoshioka H. Role of nitric oxide and reactive oxygen[corrected]species in disease resistance to necrotrophic pathogens[J]. Plant Signaling Behavior, 2010, 5（7）：872-874.
[71] Mur LA, Laarhoven LJ, Harren FJ, et al. Nitric oxide interacts with salicylate to regulate biphasic ethylene production during the hypersensitive response[J]. Plant Physiology, 2008, 148（3）：1537-1546.
[72] Mason MG, Botella JR. Completing the heterotrimer：isolationand characterization of an Arabidopsis thaliana G protein γ-subunit cDNA[J]. Proceedings of the National Academy of Sciences USA, 2000, 97（36）：14784-14788.
[73] Oldham WM, Hamm HE. Heterotrimeric G protein activation by G-protein-coupled receptors[J]. Molecular Cell Biology, 2008, 9（1）：60-71.
[74] Steffens B, Sauter M. Heterotrimeric G protein signaling is required for epidermal cell death in rice[J]. Plant Physiology, 2009, 151（2）：732-740.
[75] Delgado-Cerezo M, Sánchez-Rodríguez C, Escudero V, et al. Arabidopsis heterotrimeric G-protein regulates cell wall defense and resistance to necrotrophic fungi[J]. Molecular Plant, 2012, 5（1）：98-114.
[76] Okamoto H, Göbel C, Capper RG, et al. The alpha-subunit of the heterotrimeric G-protein affects jasmonate responses in Arabidopsis thaliana[J]. Journal of Experimental Botany, 2009, 60（7）：1991-2003.
[77] Ishikawa A. The Arabidopsis G-protein beta-subunit is required for defense response against Agrobacterium tumefaciens[J]. Bioscience, Biotechnology, & Biochemistry, 2009, 73（1）：47-55.
[78] Torres MA, Morales J, Sánchez-Rodríguez C, et al. Functional interplay between Arabidopsis NADPH oxidases and heterotrimeric G protein[J]. Molecular Plant-Microbe Interactions, 2013, 26（6）：686-694.
[79] Liu J, Ding P, Sun T, et al. Heterotrimeric G proteins serve as a converging point in plant defense signaling activated by multiple receptor-like kinases[J]. Plant Physiology, 2013, 161（4）：2146-2158.