The Latest Research Progress on CRISPR/Cas System

doi:10.13560/j.cnki.biotech.bull.1985.2017.02.008

Abstract

Abstract: The CRISPR/Cas is a system of immune mechanism for bacteria and archaea against exogenous virus and plasmid DNA invasion. As a novel genome editing technology,it possesses the advantages of a simple design,strong specificity,and high efficiency,bringing revolutionary breakthrough for genome directional modification,regulation and application. We introduce the research background,the existence type of the CRISPR/Cas system,and basic action mechanism of Type II and Type III CRISPR system and new research breakthrough in detailed,for providing the reference for readers and researchers in related fields.

Key words: genome editing technology, CRISPR/Cas system, Cas9, scRNA

LIU Ni, LU Qin, LIU Juan, CHEN Hang. The Latest Research Progress on CRISPR/Cas System[J]. Biotechnology Bulletin, 2017, 33(2): 53-58.

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