Biotechnology Bulletin ›› 2013, Vol. 0 ›› Issue (9): 43-46.

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Progress of IGFs and Its Signaling Pathway

Li Cong1,Ma Kaili1,Liu Zengli2,Wang Zhigang1   

  1. 1. College of Life Science,Inner Mongolia University,Hohhot 010021;
    2. The Sixth Middle School of Hohhot,Hohhot 010021
  • Received:2013-05-16 Revised:2013-09-05 Online:2013-09-05 Published:2013-09-06

Abstract: Insulin-like growth factors(IGFs)is a multifunctional growth factor family, and plays an important role in cell growth, differentiation and apoptosis. This article reviewed progress in the IGFs research, including component, molecular structure and function, signaling pathway and role in disease development in recent years. Therefore, this review provides an overview of achievements about IGFs and provides some useful data to improve research on IGFs.