细菌小RNA抗营养应激调控功能的研究进展

doi:10.13560/j.cnki.biotech.bull.1985.2016.03.003

生物技术通报 ›› 2016, Vol. 32 ›› Issue (3): 12-17.doi: 10.13560/j.cnki.biotech.bull.1985.2016.03.003

细菌小RNA抗营养应激调控功能的研究进展

付竹青¹,喻云梅²,温小军³,袁伟曦¹,赵祖国¹

1. 广东医学院微生物学与免疫学教研室, 湛江 524023；
2. 解放军第422中心医院, 湛江 524023；
3. 广东医学院附属医院肝胆外科, 湛江 524023

收稿日期:2015-05-12 出版日期:2016-03-24 发布日期:2016-03-25
作者简介:付竹青, 女, 硕士研究生, 研究方向：细菌中小RNA研究；E-mail：zhuziwell@163.com
基金资助:
国家自然科学基金项目(30901286), 东莞市社会科技发展项目(201350715200246)

Research Progress on Regulatory Function of Bacterial Small RNA Resistance to Nutritional Stress

FU Zhu-qing¹, YU Yun-mei², WEN Xiao-jun³, YUAN Wei-xi¹, ZHAO Zu-guo¹

1. Department of Microbiology and Immunology, Guangdong Medical College, Zhanjiang 524023；
2. Central Hospital of PLA, Zhanjiang 524023；
3. Hepatobiliary Surgery, Affiliated Hospital of Guangdong Medical College, Zhanjiang 524023

Received:2015-05-12 Published:2016-03-24 Online:2016-03-25

摘要/Abstract

摘要： 细菌生存的环境复杂多变, 经常处于营养元素过剩或缺乏的状态。因此, 细菌必须及时准确地调节其基因表达以适应不断变化的营养环境, 才能得以生存。小RNA(small RNA, sRNA)是近年来在细菌中发现的一类RNA调控子, 在细菌应对营养应激的基因表达调控中发挥重要作用。就细菌sRNA的特点及其抗营养应激的作用进行综述。

关键词: 细菌小RNA, 调控网络, 营养应激

Abstract: The survival environment of bacteria is complex and volatile, and it is usually in a state of over-nutrition or denutrition. Therefore, bacteria only are able to survive by using sophisticated regulation system to timely and accurately adjust its gene expressions to adapt to the changing nutritional environment. Bacterial small RNA(small RNA, sRNA)playing an important role in regulating expression of bacterial gene in response to nutrient stress, is a class of RNA regulators discovered in bacteria in recent years. This article reviews the characters and the functions of bacterial small RNA resistance to nutrient stress.

Key words: bacterial small RNA, regulatory networks, nutrient stress

付竹青,喻云梅,温小军,袁伟曦,赵祖国. 细菌小RNA抗营养应激调控功能的研究进展[J]. 生物技术通报, 2016, 32(3): 12-17.

FU Zhu-qing, YU Yun-mei, WEN Xiao-jun, YUAN Wei-xi, ZHAO Zu-guo. Research Progress on Regulatory Function of Bacterial Small RNA Resistance to Nutritional Stress[J]. Biotechnology Bulletin, 2016, 32(3): 12-17.

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细菌小RNA抗营养应激调控功能的研究进展

Research Progress on Regulatory Function of Bacterial Small RNA Resistance to Nutritional Stress

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