药用植物microRNA研究现状与展望

doi:10.13560/j.cnki.biotech.bull.1985.2019-0098

摘要/Abstract

摘要： microRNA（miRNA）是一类由内源基因编码的长度约为22个核苷酸的非编码单链RNA分子,通过切割靶mRNA和抑制mRNA翻译,可在动植物中发挥重要的调控作用。自2002年首次出现植物miRNA的报道后,植物miRNA的研究迅速成为植物分子生物学领域的研究热点。综述了植物miRNA的生物形成途径和作用机制,重点概述了药用植物中miRNA的研究现状,并对该领域未来的研究方向进行展望,以期为今后药用植物中 miRNA的研究提供参考。

关键词: miRNA, 药用植物, 生物合成途径, 鉴定和验证

Abstract: MicroRNAs（miRNAs）are endogenous ~22 nt non-encoding single-strand RNAs and may play important regulatory roles in animals and plants by targeting mRNAs for cleavage or translational repression. The study of plant miRNA has rapidly become a research hotspot in the field of plant molecular biology since the plant miRNA was first reported in 2002. This paper reviews the biogenesis and mechanism of plant miRNAs,focusing on research progress of miRNA in medicinal plants. Moreover,the paper prospects the future research direction in this field,aiming to provide references for future research of miRNA in medicinal plants.

Key words: miRNA, medicinal plants, biosynthetic pathway, identification and verification

严武平, 吴友根, 于靖, 杨东梅, 张军锋. 药用植物microRNA研究现状与展望[J]. 生物技术通报, 2019, 35(8): 178-185.

YAN Wu-ping, WU You-gen, YU Jing ,YANG Dong-mei, ZHANG Jun-feng. Research Progress and Prospect of microRNA in Medicinal Plants[J]. Biotechnology Bulletin, 2019, 35(8): 178-185.

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