Wnt信号通路与无脊椎动物天然免疫

doi:10.13560/j.cnki.biotech.bull.1985.2020-1073

摘要/Abstract

摘要：

Wnt作为一条保守的信号通路,其在不同生物过程中的作用已被广泛研究。相比脊椎动物,天然免疫在缺乏获得性免疫的无脊椎动物中显得尤为重要。近年来,由于Wnt信号通路在脊椎动物免疫中的功能被逐渐挖掘,其在无脊椎动物天然免疫中的作用引发越来越多的关注。对Wnt信号通路及其在无脊椎动物天然免疫中的重要作用进行了综述,旨为无脊椎动物的疾病防治提供新思路。

关键词: Wnt信号通路, 无脊椎动物, 天然免疫

Abstract:

As a conserved signaling pathway,Wnt has been widely studied in different biological processes. Compared with vertebrates,innate immunity in invertebrates that lack acquired immunity is particularly important. In recent years,Wnt signaling pathway in vertebrate immunity has been widely investigated,and its role in invertebrate innate immunity has attracted more and more attentions. Wnt signaling pathway and its important role in invertebrate innate immunity are reviewed to provide new clues for the diseases control of invertebrate.

Key words: Wnt signaling pathway, invertebrate, innate immunity

邹晨辰, 阮灵伟, 施泓. Wnt信号通路与无脊椎动物天然免疫[J]. 生物技术通报, 2021, 37(5): 182-196.

ZOU Chen-chen, RUAN Ling-wei, SHI Hong. Wnt Signaling Pathway and Innate Immunity of Invertebrate[J]. Biotechnology Bulletin, 2021, 37(5): 182-196.

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