生物技术通报 ›› 2014, Vol. 0 ›› Issue (1): 53-57.

• 综述与专论 • 上一篇    下一篇

共轭亚油酸诱导多种细胞凋亡

齐仁立,黄金秀,宋凡,陈英,黄萍   

  1. 重庆市畜牧科学院 农业部养猪科学重点实验室 养猪科学重庆市市级重点实验室 重庆市养猪工程技术研究中心,荣昌 402460
  • 收稿日期:2013-07-28 出版日期:2014-01-23 发布日期:2014-01-23
  • 作者简介:齐仁立, 男, 博士, 助理研究员, 研究方向: 动物脂肪代谢;E-mail: qirenli1982@163.com
  • 基金资助:
    国家“973” 计划项目(2012CB124702), 重庆市科委基本科研业务费(13426), 重庆市农发资金项目(13412)

Apoptosis of Various Cell Induced by Conjugated Linoleic Acid

Qi Renli, Huang Jinxiu, Song Fan, Chen Ying, Huang Ping   

  1. Chongqing Academy of Animal Sciences,Key Laboratory of Pig Industry Sciences,Ministry of Agriculture,Rongchang, Chongqing Key Laboratory of Pig Industry Sciences,Chongqing Engineering Research Center for Swine,Rongchang 402460
  • Received:2013-07-28 Published:2014-01-23 Online:2014-01-23

摘要: 共轭亚油酸(Conjugated linoleic acid,CLA) 是多种十八碳二烯酸异构体的统称,具有抗肿瘤,减少体脂沉积,抗#br#氧化等多种生理作用;CLA 能够通过诱导细胞凋亡实现其生理作用。针对CLA 诱导的肿瘤细胞,脂肪细胞和内皮细胞等多种细胞#br#的凋亡进行总结并加以分析,以期为相关研究提供帮助。

关键词: 共轭亚油酸, 细胞凋亡, 肿瘤细胞, 脂肪细胞

Abstract: Conjugated linoleic acid(CLA)is a family of C18 fatty acids with conjugated double bonds. The CLA have beneficial physiological effects for human and animal, such as anti-tumor, reducing body fat deposition and anti-oxidation, and also, CLA can induce cell apoptosis to exert its physiological functions. This paper summarized and discussed the cell apoptosis induced by CLA, in order to provide assistance for relative researches.

Key words: Conjugated linoleic acid, Apoptosis, Tumor cell, Adipose cell