植物bZIP参与胁迫应答调控的最新研究进展

doi:10.13560/j.cnki.biotech.bull.1985.2018-0562

摘要/Abstract

摘要： bZIP蛋白包含两个结构域,即高度保守、与DNA相结合的碱性区域,以及多样性的亮氨酸拉链,为植物中最大的转录因子家族之一。bZIP以同源或异源二聚体的形式,通过与顺式作用元件G-box、C-box、ABRE、LTRE和BoxII相结合,调控下游相关基因如ERF5、KIN1、CORl5A、COR78、CYP707A1、CYP707A3、ADS和CYP71AV1的表达。植物bZIP参与调控花的发育、种子成熟、休眠和衰老等诸多生物学过程,在盐害、干旱、冷害、渗透胁迫、机械损伤等非生物胁迫以及ABA信号的响应中担任重要作用。另外,bZIP通过水杨酸、茉莉酸及ABA信号转导通路,参与植株对虫害、病原体感染等生物胁迫的应答调控。重点综述了bZIP转录因子的结构特点、分类特征和作用机理,并对植物bZIP在生物和非生物胁迫应答中的最新研究进展进行了全面的介绍。该综述旨为后续深入探究bZIP转录因子的胁迫相关功能提供理论依据和研究思路。

关键词: bZIP, 非生物胁迫, 生物胁迫, 应答调控, 信号通路

Abstract: bZIP（basic leucine zipper）protein contains two domains,a highly conserved basic region which binds to DNA,and a diversified leucine zipper,and is one of the largest transcription factor（TF）families in plants. The homo-dimers and hetero-dimers of bZIP regulates the expressions of downstream-related genes such as ERF5,KIN1,CORl5A,COR78,CYP707A1,CYP707A3,ADS,and CYP71AV1 through binding to cis-elements G-box,C-box,ABRE,LTRE,and BoxII. Plant bZIPs are involved in the regulation of flower development,seed maturation,dormancy and senescence,and play an important role in ABA signal response and abiotic stresses such as salt damage,drought,chilling injury,osmotic stress and mechanical damage. Furthermore,bZIP is involved in the responses and regulations to biological stresses such as insect infestation and pathogen infection via salicylic acid,jasmonate and ABA signaling pathways. This paper mainly summarizes the structure characteristics,classification features and the mechanisms of bZIP,as well as the latest research progress on the responses of bZIP to biotic and abiotic stresses in plants. This review provides a theoretical basis and research ideas for further exploring the stress-related function of bZIP transcription factor.

Key words: bZIP, abiotic stress, biotic stress, response and regulation, signaling pathway

崔荣秀, 张议文, 陈晓倩, 谷彩红, 张荃. 植物bZIP参与胁迫应答调控的最新研究进展[J]. 生物技术通报, 2019, 35(2): 143-155.

CUI Rong-xiu, ZHANG Yi-wen, CHEN Xiao-qian, GU Cai-hong, ZHANG Quan. The Latest Research Progress on the Stress Responses of bZIP Involved in Plants[J]. Biotechnology Bulletin, 2019, 35(2): 143-155.

参考文献

[1] Baloglu MC, Eldem V, Hajyzadeh M, et al.Genome-wide analysis of the bZIP transcription factors in cucumber[J]. PLoS One, 2014, 9(4):e96014.
[2] Ali Z, Sarwat SS, Karim I, et al.Functions of plant’s bZIP transcription factors[J]. Pakistan Journal of Agricultural Sciences, 2016, 53(2):303-314.
[3] E ZG, Zhang YP, Zhou JH, et al. Mini review roles of the bZIP gene family in rice[J]. Genet Mol Res, 2014, 13(2):3025-3036.
[4] Riechmann JL, Heard J, Martin G, et al.Arabidopsis transcription factors:genome-wide comparative analysis among eukaryotes[J]. Science, 2000, 290(5499):2105-2110.
[5] Hwang I, Jung HJ, Park JI, et al.Transcriptome analysis of newly classified bZIP transcription factors of Brassica rapa in cold stress response[J]. Genomics, 2014, 104(3):194-202.
[6] Nijhawan A, Jain M, Tyagi AK, et al.Genomic survey and gene expression analysis of the basic leucine zipper transcription factor family in rice[J]. Plant Physiology, 2008, 146(2):333-350.
[7] Jin Z, Xu W, Liu A.Genomic surveys and expression analysis of bZIP gene family in castor bean(Ricinus communis L.)[J]. Planta, 2014, 239(2):299-312.
[8] Li YY, Meng D, Li MJ, et al.Genome-wide identification and expression analysis of the bZIP gene family in apple(Malus domestica)[J]. Tree Genetics & Genomes, 2016, 12(4):82.
[9] Li D, Fu F, Zhang H, et al.Genome-wide systematic characterization of the bZIP transcriptional factor family in tomato(Solanum lycopersicum L.)[J]. BMC Genomics, 2015, 16:771.
[10] Wang Z, Cheng K, Wan L, et al.Genome-wide analysis of the basic leucine zipper(bZIP)transcription factor gene family in six legume genomes[J]. BMC Genomics, 2015, 16:1053.
[11] Wang XL, Chen X, Yang TB, et al.Genome-wide identification of bZIP family genes Involved in drought and heat stresses in strawberry(Fragaria vesca)[J]. International Journal of Genomics, 2017, 2017:3981031.
[12] Liu JY, Chen NN, Chen F, et al.Genome-wide analysis and expression profile of the bZIP transcription factor gene family in grapevine(Vitis vinifera)[J]. BMC Genomics, 2014, 15:281.
[13] Jakoby M, Weisshaar B, Drögelaser W, et al.bZIP transcription factors in Arabidopsis[J]. Trends in Plant Science, 2002, 7(3):106-111.
[14] Gibalova A, Steinbachova L, Hafidh S, et al.Characterization of pollen-expressed bZIP protein interactions and the role of ATbZIP18 in the male gametophyte[J]. Plant Reprod, 2017, 30(1):1-17.
[15] Liao Y, Zou HF, Wei W, et al.Soybean GmbZIP44, GmbZIP62 and GmbZIP78 genes function as negative regulator of ABA signaling and confer salt and freezing tolerance in transgenic Arabidopsis[J]. Planta, 2008, 228(2):225-240.
[16] Schutze K, Harter K, Chaban C.Post-translational regulation of plant bZIP factors[J]. Trends in Plant Science, 2008, 13(5):247-255.
[17] Wang L, Zhu J, Li X, et al.Salt and drought stress and ABA responses related to bZIP genes from V. radiata and V. angularis[J]. Gene, 2018, 651:152-160.
[18] Sornaraj P, Luang S, Lopato S, et al.Basic leucine zipper(bZIP)transcription factors involved in abiotic stresses:A molecular model of a wheat bZIP factor and implications of its structure in function[J]. Biochim Biophys Acta, 2016, 1860(1 Pt A):46-56.
[19] Yoshida T, Fujita Y, Maruyama K, et al.Four Arabidopsis AREB/ABF transcription factors function predominantly in gene expression downstream of SnRK2 kinases in abscisic acid signalling in response to osmotic stress[J]. Plant Cell and Environment, 2015, 38(1):35-49.
[20] Nie X, Ji X, Liu Y, et al.Elucidation of the specific formation of homo- and heterodimeric forms of ThbZIP1 and its role in stress[J]. International Journal of Molecular Sciences, 2014, 15(6):10005-10017.
[21] Golldack D, Li C, Mohan H, et al.Tolerance to drought and salt stress in plants:Unraveling the signaling networks[J]. Frontiers in Plant Science, 2014, 5:151.
[22] Liu J, Srivastava R, Che P, et al.Salt stress in Arabidopsis utilize a signal transduction pathway related to endoplasmic reticulum stress signaling[J]. Plant Journal, 2007, 51(5):897-909.
[23] Tang W, Page M, Fei YJ, et al.Overexpression of AtbZIP60deltaC gene alleviates salt-induced oxidative damage in transgenic cell cultures[J]. Plant Molecular Biology Reporter, 2012, 30(5):1183-1195.
[24] Liu C, Mao B, Ou S, et al.OsbZIP71, a bZIP transcription factor, confers salinity and drought tolerance in rice[J]. Plant Mol Biol, 2014, 84(1/2):19-36.
[25] Zhang S, Haider I, Kohlen W, et al.Function of the HD-Zip I gene Oshox22 in ABA-mediated drought and salt tolerances in rice[J]. Plant Molecular Biology, 2012, 80(6):571-585.
[26] Lakra N, Nutan KK, Das P, et al.A nuclear-localized histone-gene binding protein from rice(OsHBP1b)functions in salinity and drought stress tolerance by maintaining chlorophyll content and improving the antioxidant machinery[J]. Journal of Plant Physiology, 2015, 176:36-46.
[27] Zhao Y, Ma Q, Jin X, et al.A novel maize homeodomain-leucine zipper(HD-Zip)I gene, Zmhdz10, positively regulates drought and salt tolerance in both rice and Arabidopsis[J]. Plant Cell Physiology, 2014, 55(6):1142-1156.
[28] Oh SK, Yoon J, Choi GJ, et al.Capsicum annuum homeobox 1(CaHB1)is a nuclear factor that has roles in plant development, salt tolerance, and pathogen defense[J]. Biochemical and Biophysical Research Communications, 2013, 442(1/2):116-121.
[29] Kumar J, Singh S, Singh M, et al.Transcriptional regulation of salinity stress in plants:A short review[J]. Plant Gene, 2017, 11:160-169.
[30] Zhang M, Liu Y, Shi, H, et al.Evolutionary and expression analyses of soybean basic leucine zipper transcription factor family[J]. BMC Genomics, 2018, 19(1):159.
[31] Guo Y, Huang R, Duan L, et al.The APETALA2/ethylene-responsive factor transcription factor OsDERF2 negatively modulates drought stress in rice by repressing abscisic acid responsive genes[J]. Journal of Agricultural Science, 2017, 155(6):1-12.
[32] Manavella PA, Arce AL, Dezar CA, et al.Cross-talk between ethylene and drought signalling pathways is mediated by the sunflower Hahb-4 transcription factor[J]. Plant Journal, 2006, 48(1):125-137.
[33] An X, Chen J, Zhang J, et al.Transcriptome profiling and identification of transcription factors in ramie(Boehmeria nivea L. Gaud)in response to PEG treatment, using illumina paired-end sequencing technology[J]. International Journal of Molecular Sciences, 2015, 16(2):3493-3511.
[34] Chinnusamy V, Zhu JH, Zhu JK.Gene regulation during cold acclimation in plants[J]. Physiologia Plantarum, 2006, 126(1):52-61.
[35] Cai W, Yang Y, Wang W, et al.Overexpression of a wheat(Tritic-um aestivum L.)bZIP transcription factor gene, TabZIP6, decreased the freezing tolerance of transgenic Arabidopsis seedlings by down-regulating the expression of CBFs[J]. Plant Physiol Biochem, 2018, 124:100-111.
[36] Banerjee A, Roychoudhury A.Abscisic-acid-dependent basic leucine zipper(bZIP)transcription factors in plant abiotic stress[J]. Protoplasma, 2017, 254(1):3-16.
[37] Liu C, Wu Y, Wang X. bZIP transcription factor OsbZIP52/RISBZ5:a potential negative regulator of cold and drought stress response in rice[J]. Planta, 2012, 235(6):1157-1169.
[38] Ito K, Kusano T, Tsutsumi KI.A cold-inducible bZIP protein gene in radish root regulated by calcium- and cycloheximide-mediated signals[J]. Plant Science, 1999, 142:57-65.
[39] Zhang Z, Chen X, Guan X, et al.A genome-wide survey of homeodomain-leucine zipper genes and analysis of cold-responsive HD-Zip I members expression in tomato[J]. Bioscience Biotechnology and Biochemistry, 2014, 78(8):1337-1349.
[40] Veerabagu M, Kirchler T, Elgass K, et al.The interaction of the Arabidopsis response regulator ARR18 with bZIP63 mediates the regulation of PROLINE DEHYDROGENASE expression[J]. Molecular Plant, 2014, 7(10):1560-1577.
[41] Tsugama D, Liu S, Takano T.The bZIP protein VIP1 is involved in touch responses in Arabidopsis roots[J]. Plant Physiology, 2016, 171(2):1355-1365.
[42] Leene JV, Blomme J, Kulkarni SR, et al.Functional characterization of the Arabidopsis transcription factor bZIP29 reveals its role in leaf and root development[J]. Journal of Experimental Botany, 2016, 67(19):5825-5840.
[43] Cao L, Yu Y, Chen C, et al.A novel Glycine soja homeodomain-leucine zipper(HD-Zip)I gene, Gshdz4, positively regulates bicarbonate tolerance and responds to osmotic stress in Arabidopsis[J]. BMC Plant Biology, 2016, 16(1):184.
[44] Hossain MA, Cho JI, Han M, et al.The ABRE-binding bZIP transcription factor OsABF2 is a positive regulator of abiotic stress and ABA signaling in rice[J]. Journal of Plant Physiology, 2010, 167(17):1512-1520.
[45] Zhang F, Fu X, Lv Z, et al.A basic leucine zipper transcription factor, AabZIP1, connects abscisic acid signaling with artemisinin biosynthesis in Artemisia annua[J]. Molecular Plant, 2015, 8(1):163-175.
[46] Re DA, Dezar CA, Chan RL, et al.Nicotiana attenuata NaHD20 plays a role in leaf ABA accumulation during water stress, benzylacetone emission from flowers, and the timing of bolting and flower transitions[J]. Journal of Experimental Botany, 2011, 62(1):155-166.
[47] Lertpanyasampatha M, Viboonjun U, Kongsawadworakul P, et al.Differential expression of microRNAs and their targets reveals a possible dual role in physiological bark disorder in rubber tree[J]. Journal of Plant Physiology, 2014, 171(13):1117-1126.
[48] Amorim LL, Da FDSR, Guida-Santos M, et al.Transcription factors involved in plant resistance to pathogens[J]. Current Protein & Peptide Science, 2017, 18(4):335-351.
[49] Meng XB, Zhao WS, Lin RM, et al.Identification of a novel rice bZIP-type transcription factor gene, OsbZIP1, involved in response to infection of Magnaporthe grisea[J]. Plant Molecular Biology Reporter, 2005, 23(3):301-302.
[50] Zhang Y, Zhang G, Xia N, et al.Cloning and characterization of a bZIP transcription factor gene in wheat and its expression in response to stripe rust pathogen infection and abiotic stresses[J]. Physiological and Molecular Plant Pathology, 2008, 73(4/5):88-94.
[51] Lee SC, Choi HW, Hwang IS, et al.Functional roles of the pepper pathogen-induced bZIP transcription factor, CAbZIP1, in enhanced resistance to pathogen infection and environmental stresses[J]. Planta, 2006, 224(5):1209-1225.
[52] Dezar CA, Giacomelli JI, Manavella PA, et al.HAHB10, a sunflower HD-Zip II transcription factor, participates in the induction of flowering and in the control of phytohormone-mediated responses to biotic stress[J]. Journal of Experimental Botany, 2011, 62(3):1061-1076.
[53] Rabara RC, Tripathi P, Rushton PJ.The potential of transcription factor-based genetic engineering in improving crop tolerance to drought[J]. OMICS, 2014, 18(10):601-614.
[54] Gao D, Appiano M, Huibers RP, et al.Activation tagging of ATHB13 in Arabidopsis thaliana confers broad-spectrum disease resistance[J]. Plant Molecular Biology, 2014, 86(6):641-653.
[55] Kaminaka H, Näke C, Epple P, et al.bZIP10-LSD1 antagonism modulates basal defense and cell death in Arabidopsis following infection[J]. Embo Journal, 2006, 25(18):4400-4411.
[56] Manavella PA, Dezar CA, Bonaventure G, et al.HAHB4, a sunflower HD-Zip protein, integrates signals from the jasmonic acid and ethylene pathways during wounding and biotic stress responses[J]. Plant Journal for Cell and Molecular Biology, 2010, 56(3):376-388.
[57] Llorca CM, Potschin M, Zentgraf U. bZIPs and WRKYs:two large transcription factor families executing two different functional strategies[J]. Frontiers in Plant Science, 2014, 5:169.
[58] Gruber V, Blanchet S, Diet A, et al.Identification of transcription factors involved in root apex responses to salt stress in Medicago truncatula[J]. Mol Genet Genomics, 2009, 281(1):55-66.