生物技术通报 ›› 2020, Vol. 36 ›› Issue (8): 228-234.doi: 10.13560/j.cnki.biotech.bull.1985.2020-0014
孙嘉栋, 孙晓凤, 李兰, 沈伟, 程顺峰
收稿日期:
2020-01-04
出版日期:
2020-08-26
发布日期:
2020-08-27
作者简介:
孙嘉栋,男,硕士,研究方向:发育生物学;E-mail:sun-jiadong@163.com
基金资助:
SUN Jia-dong, SUN Xiao-feng, LI Lan, SHEN Wei, CHENG Shun-feng
Received:
2020-01-04
Published:
2020-08-26
Online:
2020-08-27
摘要: 我国是养猪大国,拥有全球1/3猪种质资源。但近年来,我国地方品种猪养殖量急剧减少,部分品种几近灭绝,地方猪种遗传资源多样性遭受严重破坏,优质基因不断流失。如何有效保护和保存这些优良种质资源是非常紧迫和关键的问题。目前猪种质资源保护包括原位保存、精液和胚胎冷冻保存、DNA文库保种和体细胞冷冻保存等,但都存在一定局限性。干细胞是一类可以自我更新并具有分化潜能的细胞群体,它不仅能分化成不同类型的细胞,还可以通过分裂维持自身群体稳定。在小鼠和猪等动物上,利用干细胞已成功获得健康后代。最近,以干细胞研究为引领的种质资源保护新浪潮正在兴起,干细胞技术将成为我国地方猪种质资源保护的新手段。
孙嘉栋, 孙晓凤, 李兰, 沈伟, 程顺峰. 干细胞技术在地方猪种质资源保护中的应用前景[J]. 生物技术通报, 2020, 36(8): 228-234.
SUN Jia-dong, SUN Xiao-feng, LI Lan, SHEN Wei, CHENG Shun-feng. Application Prospects of Stem Cell Technology in the Protection of Indigenous Porcine Germplasm Resources[J]. Biotechnology Bulletin, 2020, 36(8): 228-234.
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