bHLH转录因子的磷酸化调控植物生理功能的研究进展

doi:10.13560/j.cnki.biotech.bull.1985.2022-0775

摘要/Abstract

摘要：

bHLH转录因子是植物体内第二大类转录因子，在植物生长发育和胁迫反应的转录调控网络中扮演着非常重要的角色。磷酸化作为蛋白质翻译后重要的调控方式，影响转录因子的转录活性、定位、蛋白间互作、稳定性。为深入了解磷酸化对bHLH转录因子的影响，本文对近年来bHLH家族成员的磷酸化研究进展进行综述，包括bHLH转录因子的结构、分类、功能以及磷酸化位点上的突变对其生理及生化功能的改变，为从磷酸化调控角度提升农作物的营养利用效率、品质和抗逆性等农艺性状提供理论依据。

关键词: 碱性螺旋-环-螺旋转录因子, 磷酸化, 生理功能

Abstract:

bHLH（basic Helix-Loop-Helix）is the second largest class of transcription factors in plants and plays an important role in the transcriptional regulatory network of plant growth and development and stress responses. Protein phosphorylation as a quick and flexible posttranslational modification affects the transcriptional activity, localization, protein interaction and stability of transcription factors. To understand the multifaceted roles of bHLH phosphorylation, here we review recent advances in the phosphorylation of bHLH family members, including the structure, classification, and function of the bHLH transcription factors, as well as the changing of their physiological and biochemical function caused by mutations at the phosphorylation sites, aiming to provide theoretical basis for improving agronomic traits such as nutrient use efficiency, quality and stress tolerance from the perspective of phosphorylation regulation.

Key words: transcription factor bHLH, phosphorylation, physiological function

刘铖霞, 孙宗艳, 罗云波, 朱鸿亮, 曲桂芹. bHLH转录因子的磷酸化调控植物生理功能的研究进展[J]. 生物技术通报, 2023, 39(3): 26-34.

LIU Cheng-xia, SUN Zong-yan, LUO Yun-bo, ZHU Hong-liang, QU Gui-qin. Multifaceted Roles of bHLH Phosphorylation in Regulation of Plant Physiological Functions[J]. Biotechnology Bulletin, 2023, 39(3): 26-34.

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