小肽激素调控植物生长发育及逆境生理研究进展

doi:10.13560/j.cnki.biotech.bull.1985.2022-1468

生物技术通报 ›› 2023, Vol. 39 ›› Issue (7): 13-25.doi: 10.13560/j.cnki.biotech.bull.1985.2022-1468

小肽激素调控植物生长发育及逆境生理研究进展

胡海琳¹^,²^,³^,⁴(), 徐黎¹^,²^,³^,⁴, 李晓旭¹^,²^,³^,⁴, 王晨璨¹^,²^,³^,⁴, 梅曼¹^,²^,³^,⁴, 丁文静¹^,²^,³^,⁴, 赵媛媛¹^,²^,³^,⁴()

1.北京林业大学生物科学与技术学院林木遗传育种全国重点实验室，北京 100083
2.北京林业大学生物科学与技术学院，北京 100083
3.北京林业大学树木与基因编辑研究院，北京 100083
4.北京林业大学林木育种与生态修复国家工程研究中心，北京 100083

收稿日期:2022-11-29 出版日期:2023-07-26 发布日期:2023-08-17
通讯作者: 赵媛媛，女，博士，副教授，研究方向：木本植物生长发育；E-mail: yyzhao@bjfu.edu.cn
作者简介:胡海琳，女，硕士研究生，研究方向：木本植物生长发育；E-mail: huhailin@bjfu.edu.cn
第一联系人：徐黎为本文共同第一作者
基金资助:
国家自然科学基金项目(31870571)

Advances in the Regulation of Plant Growth, Development and Stress Physiology by Small Peptide Hormones

HU Hai-lin¹^,²^,³^,⁴(), XU Li¹^,²^,³^,⁴, LI Xiao-xu¹^,²^,³^,⁴, WANG Chen-can¹^,²^,³^,⁴, MEI Man¹^,²^,³^,⁴, DING Wen-jing¹^,²^,³^,⁴, ZHAO Yuan-yuan¹^,²^,³^,⁴()

1. State Key Laboratory of Tree Genetics and Breeding, College of Biological Sciences and Technology, Beijing Forestry University, Beijing 100083
2. College of Biological Sciences and Biotechnology, Beijing Forestry University, Beijing 100083
3. Institute of Tree and Genome Editing, Beijing Forestry University, Beijing 100083
4. National Engineering Research Center of Tree Breeding and Ecological Restoration, Beijing Forestry University, Beijing 100083

Received:2022-11-29 Published:2023-07-26 Online:2023-08-17

摘要/Abstract

摘要：

小肽激素通常是指含5-100个氨基酸长度的肽段。在植物体内小肽激素含量很低、分子量小、数量多、来源及加工成熟机制复杂，这赋予了小肽多种多样的生物学功能，能够在极低浓度下与受体结合，调节植物的细胞分裂与生长、组织与器官分化、开花与结实、成熟与衰老等生理过程，协调植物响应多种胁迫环境。小肽激素作为细胞间信号转导的重要介质，参与调控生长发育的分子机制是近年来植物学科研究的热点和前沿。本文系统综述了小肽激素的结构、分类及其功能研究进展，重点讨论了CLE、RALFs、PSK、CIF、SYS等家族调控植物生长发育及逆境生理的研究进展，并展望了植物小肽激素的应用前景，为植物小肽激素的深层次研究和开发应用提供了重要的理论基础。

关键词: 小肽激素, 受体, 生长发育, 逆境生理, CLE, RALFs, PSK, CIF

Abstract:

Small peptide hormones are usually referred to as peptides containing 5 to 100 amino acids in length. In plants, the contents of small peptide hormones are very low, the molecular weight is small, the quantity is large, and the source and processing mechanism is complex. This gives small peptides a variety of biological functions. They can bind to receptors at very low concentrations, regulate physiological processes such as cell division and growth, tissue and organ differentiation, flowering and fruiting, maturation and senescence, and coordinate plant responses to various stress environments. As an important medium of signal transduction among cells, the molecular mechanism of small peptide hormones in regulating growth and development is the hotspot and front topic in Botany. First the research progress of the structure, synthesis, classification and function of small peptide hormones were systematically reviewed. Furthermore, the research progress of CIF, CLE, RALFs, PSK, SYS in regulating plant growth and development and stress physiology was emphatically summarized, and the application prospect of plant small peptide hormones was outlined, which may provide an important theoretical basis for the in-depth research, development and application of plant small peptide hormones.

Key words: small peptide hormones, receptor, growth and development, stress physiology, CLE, RALFs, PSK, CIF

胡海琳, 徐黎, 李晓旭, 王晨璨, 梅曼, 丁文静, 赵媛媛. 小肽激素调控植物生长发育及逆境生理研究进展[J]. 生物技术通报, 2023, 39(7): 13-25.

HU Hai-lin, XU Li, LI Xiao-xu, WANG Chen-can, MEI Man, DING Wen-jing, ZHAO Yuan-yuan. Advances in the Regulation of Plant Growth, Development and Stress Physiology by Small Peptide Hormones[J]. Biotechnology Bulletin, 2023, 39(7): 13-25.

图/表 3

参考文献 106

[1]	Busch W, Benfey PN. Information processing without brains—the power of intercellular regulators in plants[J]. Development, 2010, 137(8): 1215-1226. doi: 10.1242/dev.034868 URL
[2]	李文凤, 兰平. 植物小肽研究进展I:来源、鉴定和调控[J]. 土壤, 2019, 51(6): 1049-1056.
	Li WF, Lan P. Research progress of plant signal peptide: origin, identification and regulation[J]. Soils, 2019, 51(6): 1049-1056.
[3]	Djordjevic MA, Mohd-Radzman NA, Imin N. Small-peptide signals that control root nodule number, development, and symbiosis[J]. J Exp Bot, 2015, 66(17): 5171-5181. doi: 10.1093/jxb/erv357 pmid: 26249310
[4]	Imin N, Mohd-Radzman NA, Ogilvie HA, et al. The peptide-encoding CEP1 gene modulates lateral root and nodule numbers in Medicago truncatula[J]. J Exp Bot, 2013, 64(17): 5395-5409. doi: 10.1093/jxb/ert369 URL
[5]	Nakayama T, Shinohara H, Tanaka M, et al. A peptide hormone required for Casparian strip diffusion barrier formation in Arabidopsis roots[J]. Science, 2017, 355(6322): 284-286. doi: 10.1126/science.aai9057 pmid: 28104889
[6]	Li XX, Salman A, Guo C, et al. Identification and characterization of LRR-RLK family genes in potato reveal their involvement in peptide signaling of cell fate decisions and biotic/abiotic stress responses[J]. Cells, 2018, 7(9): 120. doi: 10.3390/cells7090120 URL
[7]	De Smet I, Voss U, Jürgens G, et al. Receptor-like kinases shape the plant[J]. Nat Cell Biol, 2009, 11(10): 1166-1173. doi: 10.1038/ncb1009-1166 pmid: 19794500
[8]	Pearce G, Strydom D, Johnson S, et al. A polypeptide from tomato leaves induces wound-inducible proteinase inhibitor proteins[J]. Science, 1991, 253(5022): 895-897. doi: 10.1126/science.253.5022.895 pmid: 17751827
[9]	Hsu PY, Benfey PN. Small but mighty: functional peptides encoded by small ORFs in plants[J]. Proteomics, 2018, 18(10): e1700038.
[10]	Tavormina P, De Coninck B, Nikonorova N, et al. The plant peptidome: an expanding repertoire of structural features and biological functions[J]. Plant Cell, 2015, 27(8): 2095-2118. doi: 10.1105/tpc.15.00440 URL
[11]	Juntawong P, Girke T, Bazin J, et al. Translational dynamics revealed by genome-wide profiling of ribosome footprints in Arabidopsis[J]. Proc Natl Acad Sci USA, 2014, 111(1): E203-E212.
[12]	Crappé J, Van Criekinge W, Trooskens G, et al. Combining in silico prediction and ribosome profiling in a genome-wide search for novel putatively coding sORFs[J]. BMC Genomics, 2013, 14: 648. doi: 10.1186/1471-2164-14-648 pmid: 24059539
[13]	Samir P, Link AJ. Analyzing the cryptome: uncovering secret sequences[J]. AAPS J, 2011, 13(2): 152-158. doi: 10.1208/s12248-011-9252-2 pmid: 21327597
[14]	Pearce G, Munske G, Yamaguchi Y, et al. Structure-activity studies of GmSubPep, a soybean peptide defense signal derived from an extracellular protease[J]. Peptides, 2010, 31(12): 2159-2164. doi: 10.1016/j.peptides.2010.09.004 pmid: 20833217
[15]	蔺欢, 王俊娟, 孙振婷, 等. 植物小分子肽的研究进展[J]. 西北植物学报, 2021, 41(1): 168-180.
	Lin H, Wang JJ, Sun ZT, et al. The research progress of plant small molecular peptides[J]. Acta Bot Boreali Occidentalia Sin, 2021, 41(1): 168-180.
[16]	Patel N, Mohd-Radzman NA, Corcilius L, et al. Diverse peptide hormones affecting root growth identified in the Medicago truncatula secreted peptidome[J]. Mol Cell Proteomics, 2018, 17(1): 160-174. doi: 10.1074/mcp.RA117.000168 pmid: 29079721
[17]	Meng L, Buchanan BB, Feldman LJ, et al. A putative nuclear CLE-like(CLEL)peptide precursor regulates root growth in Arabidopsis[J]. Mol Plant, 2012, 5(4): 955-957. doi: 10.1093/mp/sss060 URL
[18]	华春, 周峰, 陈全战, 等. 植物多肽信号及翻译后修饰小肽[J]. 湖北农业科学, 2015, 54(15): 3585-3589.
	Hua C, Zhou F, Chen QZ, et al. Plant peptide signal and post-translationally modified small-peptide signals[J]. Hubei Agric Sci, 2015, 54(15): 3585-3589.
[19]	Zhang HY, Zhang H, Lin JX. Systemin-mediated long-distance systemic defense responses[J]. New Phytol, 2020, 226(6): 1573-1582. doi: 10.1111/nph.16495 pmid: 32083726
[20]	Stintzi A, Schaller A. Biogenesis of post-translationally modified peptide signals for plant reproductive development[J]. Curr Opin Plant Biol, 2022, 69: 102274. doi: 10.1016/j.pbi.2022.102274 URL
[21]	Murphy E, Smith S, De Smet I. Small signaling peptides in Arabidopsis development: how cells communicate over a short distance[J]. Plant Cell, 2012, 24(8): 3198-3217. doi: 10.1105/tpc.112.099010 URL
[22]	Pearce G, Ryan CA. Systemic signaling in tomato plants for defense against herbivores. Isolation and characterization of three novel defense-signaling glycopeptide hormones coded in a single precursor gene[J]. J Biol Chem, 2003, 278(32): 30044-30050. doi: 10.1074/jbc.M304159200 pmid: 12748180
[23]	Doblas VG, Smakowska-Luzan E, Fujita S, et al. Root diffusion barrier control by a vasculature-derived peptide binding to the SGN3 receptor[J]. Science, 2017, 355(6322): 280-284. doi: 10.1126/science.aaj1562 pmid: 28104888
[24]	Fletcher JC, Brand U, Running MP, et al. Signaling of cell fate decisions by CLAVATA3 in Arabidopsis shoot meristems[J]. Science, 1999, 283(5409): 1911-1914. doi: 10.1126/science.283.5409.1911 pmid: 10082464
[25]	Butenko MA, Patterson SE, Grini PE, et al. Inflorescence deficient in abscission controls floral organ abscission in Arabidopsis and identifies a novel family of putative ligands in plants[J]. Plant Cell, 2003, 15(10): 2296-2307. doi: 10.1105/tpc.014365 URL
[26]	Tinoco AD, Kim YG, Tagore DM, et al. A peptidomics strategy to elucidate the proteolytic pathways that inactivate peptide hormones[J]. Biochemistry, 2011, 50(12): 2213-2222. doi: 10.1021/bi2000033 pmid: 21299233
[27]	Tinoco AD, Saghatelian A. Investigating endogenous peptides and peptidases using peptidomics[J]. Biochemistry, 2011, 50(35): 7447-7461. doi: 10.1021/bi200417k pmid: 21786763
[28]	Chen YL, Lee CY, Cheng KT, et al. Quantitative peptidomics study reveals that a wound-induced peptide from PR-1 regulates immune signaling in tomato[J]. Plant Cell, 2014, 26(10): 4135-4148. doi: 10.1105/tpc.114.131185 URL
[29]	Matsuzaki Y, Ogawa-Ohnishi M, Mori A, et al. Secreted peptide signals required for maintenance of root stem cell niche in Arabidopsis[J]. Science, 2010, 329(5995): 1065-1067. doi: 10.1126/science.1191132 pmid: 20798316
[30]	Ohyama K, Ogawa M, Matsubayashi Y. Identification of a biologically active, small, secreted peptide in Arabidopsis by in silico gene screening, followed by LC-MS-based structure analysis[J]. Plant J, 2008, 55(1): 152-160. doi: 10.1111/tpj.2008.55.issue-1 URL
[31]	Ghorbani S, Lin YC, Parizot B, et al. Expanding the repertoire of secretory peptides controlling root development with comparative genome analysis and functional assays[J]. J Exp Bot, 2015, 66(17): 5257-5269. doi: 10.1093/jxb/erv346 pmid: 26195730
[32]	Constabel CP, Yip L, Ryan CA. Prosystemin from potato, black nightshade, and bell pepper: primary structure and biological activity of predicted systemin polypeptides[J]. Plant Mol Biol, 1998, 36(1): 55-62. doi: 10.1023/a:1005986004615 pmid: 9484462
[33]	Bücherl CA, Jarsch IK, Schudoma C, et al. Plant immune and growth receptors share common signalling components but localise to distinct plasma membrane nanodomains[J]. eLife, 2017, 6: e25114.
[34]	Goad DM, Zhu CM, Kellogg EA. Comprehensive identification and clustering of CLV3/ESR-related(CLE)genes in plants finds groups with potentially shared function[J]. New Phytol, 2017, 216(2): 605-616. doi: 10.1111/nph.2017.216.issue-2 URL
[35]	Reichardt S, Piepho HP, Stintzi A, et al. Peptide signaling for drou-ght-induced tomato flower drop[J]. Science, 2020, 367(6485): 1482-1485. doi: 10.1126/science.aaz5641 pmid: 32217727
[36]	Rodriguez-Villalon A. Wiring a plant: genetic networks for phloem formation in Arabidopsis thaliana roots[J]. New Phytol, 2016, 210(1): 45-50. doi: 10.1111/nph.13527 pmid: 26171671
[37]	Fletcher JC. Recent advances in Arabidopsis CLE peptide signaling[J]. Trends Plant Sci, 2020, 25(10): 1005-1016. doi: 10.1016/j.tplants.2020.04.014 URL
[38]	Brand U, Fletcher JC, Hobe M, et al. Dependence of stem cell fate in Arabidopsis on a feedback loop regulated by CLV3 activity[J]. Science, 2000, 289(5479): 617-619. doi: 10.1126/science.289.5479.617 pmid: 10915624
[39]	Zhang LS, Shi X, Zhang YT, et al. CLE 9 peptide-induced stomatal closure is mediated by abscisic acid, hydrogen peroxide, and nitric oxide in Arabidopsis thaliana[J]. Plant Cell Environ, 2019, 42(3): 1033-1044. doi: 10.1111/pce.v42.3 URL
[40]	Fujita S. CASPARIAN STRIP INTEGRITY FACTOR(CIF)family peptides - regulator of plant extracellular barriers[J]. Peptides, 2021, 143: 170599. doi: 10.1016/j.peptides.2021.170599 URL
[41]	Truskina J, Brück S, Stintzi A, et al. A peptide-mediated, multilateral molecular dialogue for the coordination of pollen wall formation[J]. Proc Natl Acad Sci USA, 2022, 119(22): e2201446119.
[42]	Yang H, Matsubayashi Y, Hanai H, et al. Phytosulfokine-alpha, a peptide growth factor found in higher plants: its structure, functions, precursor and receptors[J]. Plant Cell Physiol, 2000, 41(7): 825-830. pmid: 10965938
[43]	Stührwohldt N, Dahlke RI, Steffens B, et al. Phytosulfokine-α controls hypocotyl length and cell expansion in Arabidopsis thaliana through phytosulfokine receptor 1[J]. PLoS One, 2011, 6(6): e21054.
[44]	Wang C, Yu HX, Zhang ZM, et al. Phytosulfokine is involved in positive regulation of lotus japonicus nodulation[J]. Mol Plant Microbe Interact, 2015, 28(8): 847-855. doi: 10.1094/MPMI-02-15-0032-R URL
[45]	Stührwohldt N, Bühler E, Sauter M, et al. Phytosulfokine(PSK)precursor processing by subtilase SBT3.8 and PSK signaling improve drought stress tolerance in Arabidopsis[J]. J Exp Bot, 2021, 72(9): 3427-3440. doi: 10.1093/jxb/erab017 pmid: 33471900
[46]	Liu YM, Zhang DP, Li M, et al. Overexpression of PSK-γ in Arabidopsis promotes growth without influencing pattern-triggered immunity[J]. Plant Signal Behav, 2019, 14(12): 1684423. doi: 10.1080/15592324.2019.1684423 URL
[47]	Yu LL, Di Q, Zhang DP, et al. A legume-specific novel type of phytosulfokine, PSK-δ, promotes nodulation by enhancing nodule organogenesis[J]. J Exp Bot, 2022, 73(8): 2698-2713. doi: 10.1093/jxb/erac051 pmid: 35137020
[48]	Blackburn MR, Haruta M, Moura DS. Twenty years of progress in physiological and biochemical investigation of RALF peptides[J]. Plant Physiol, 2020, 182(4): 1657-1666. doi: 10.1104/pp.19.01310 pmid: 32071151
[49]	Pearce G, Moura DS, Stratmann J, et al. RALF, a 5-kDa ubiquitous polypeptide in plants, arrests root growth and development[J]. Proc Natl Acad Sci USA, 2001, 98(22): 12843-12847. pmid: 11675511
[50]	Matos JL, Fiori CS, Silva-Filho MC, et al. A conserved dibasic site is essential for correct processing of the peptide hormone AtRALF1 in Arabidopsis thaliana[J]. FEBS Lett, 2008, 582(23/24): 3343-3347. doi: 10.1016/j.febslet.2008.08.025 URL
[51]	Gonneau M, Desprez T, Martin M, et al. Receptor kinase THESEUS1 is a rapid alkalinization factor 34 receptor in Arabidop-sis[J]. Curr Biol, 2018, 28(15): 2452-2458.e4. doi: 10.1016/j.cub.2018.05.075 URL
[52]	Ge ZX, Zhao YL, Liu MC, et al. LLG2/3 are co-receptors in BUPS/ANX-RALF signaling to regulate Arabidopsis pollen tube integrity[J]. Curr Biol, 2019, 29(19): 3256-3265.e5. doi: 10.1016/j.cub.2019.08.032 URL
[53]	Ge ZX, Cheung AY, Qu LJ. Pollen tube integrity regulation in flowering plants: insights from molecular assemblies on the pollen tube surface[J]. New Phytol, 2019, 222(2): 687-693. doi: 10.1111/nph.15645 pmid: 30556141
[54]	Cock JM, McCormick S. A large family of genes that share homology with CLAVATA3[J]. Plant Physiol, 2001, 126(3): 939-942. doi: 10.1104/pp.126.3.939 pmid: 11457943
[55]	Casamitjana-Martínez E, Hofhuis HF, Xu J, et al. Root-specific CLE19 overexpression and the sol1/2 suppressors implicate a CLV-like pathway in the control of Arabidopsis root meristem maintenance[J]. Curr Biol, 2003, 13(16): 1435-1441. doi: 10.1016/s0960-9822(03)00533-5 pmid: 12932329
[56]	Ni J, Clark SE. Evidence for functional conservation, sufficiency, and proteolytic processing of the CLAVATA3 CLE domain[J]. Plant Physiol, 2006, 140(2): 726-733. doi: 10.1104/pp.105.072678 pmid: 16407446
[57]	Zhang Y, Tan SY, Gao YH, et al. CLE42 delays leaf senescence by antagonizing ethylene pathway in Arabidopsis[J]. New Phytol, 2022, 235(2): 550-562. doi: 10.1111/nph.18154 pmid: 35396726
[58]	Wang WP, Hu C, Li XN, et al. Receptor-like cytoplasmic kinases PBL34/35/36 are required for CLE peptide-mediated signaling to maintain shoot apical meristem and root apical meristem homeostasis in Arabidopsis[J]. Plant Cell, 2022, 34(4): 1289-1307. doi: 10.1093/plcell/koab315 URL
[59]	Roman AO, Jimenez-Sandoval P, Augustin S, et al. HSL1 and BAM1/2 impact epidermal cell development by sensing distinct signaling peptides[J]. Nat Commun, 2022, 13(1): 876. doi: 10.1038/s41467-022-28558-4
[60]	Li J, Nagpal P, Vitart V, et al. A role for brassinosteroids in light-dependent development of Arabidopsis[J]. Science, 1996, 272(5260): 398-401. doi: 10.1126/science.272.5260.398 pmid: 8602526
[61]	Lorbiecke R, Steffens M, Tomm JM, et al. Phytosulphokine gene regulation during maize(Zea mays L.) reproduction[J]. J Exp Bot, 2005, 56(417): 1805-1819. doi: 10.1093/jxb/eri169 pmid: 15897229
[62]	Hanai H, Matsuno T, Yamamoto M, et al. A secreted peptide growth factor, phytosulfokine, acting as a stimulatory factor of carrot somatic embryo formation[J]. Plant Cell Physiol, 2000, 41(1): 27-32. doi: 10.1093/pcp/41.1.27 pmid: 10750705
[63]	Kutschmar A, Rzewuski G, Stührwohldt N, et al. PSK-α promotes root growth in Arabidopsis[J]. New Phytol, 2009, 181(4): 820-831. doi: 10.1111/j.1469-8137.2008.02710.x pmid: 19076296
[64]	Hartmann J, Fischer C, Dietrich P, et al. Kinase activity and calmodulin binding are essential for growth signaling by the phytosulfokine receptor PSKR1[J]. Plant J, 2014, 78(2): 192-202. doi: 10.1111/tpj.12460 URL
[65]	Matsubayashi Y, Ogawa M, Morita A, et al. An LRR receptor kinase involved in perception of a peptide plant hormone, phytosulfokine[J]. Science, 2002, 296(5572): 1470-1472. doi: 10.1126/science.1069607 pmid: 12029134
[66]	Wang JZ, Li HJ, Han ZF, et al. Allosteric receptor activation by the plant peptide hormone phytosulfokine[J]. Nature, 2015, 525(7568): 265-268. doi: 10.1038/nature14858
[67]	Kwezi L, Ruzvidzo O, Wheeler JI, et al. The phytosulfokine(PSK)receptor is capable of guanylate cyclase activity and enabling cyclic GMP-dependent signaling in plants[J]. J Biol Chem, 2011, 286(25): 22580-22588. doi: 10.1074/jbc.M110.168823 URL
[68]	Matsubayashi Y, Ogawa M, Kihara H, et al. Disruption and overexpression of Arabidopsis phytosulfokine receptor gene affects cellular longevity and potential for growth[J]. Plant Physiol, 2006, 142(1): 45-53. doi: 10.1104/pp.106.081109 pmid: 16829587
[69]	Kaufmann C, Stührwohldt N, Sauter M. Tyrosylprotein sulfotransferase-dependent and-independent regulation of root development and signaling by PSK LRR receptor kinases in Arabidopsis[J]. J Exp Bot, 2021, 72(15): 5508-5521. doi: 10.1093/jxb/erab233 URL
[70]	Gómez BG, Holzwart E, Shi CN, et al. Phosphorylation-dependent routing of RLP44 towards brassinosteroid or phytosulfokine signalling[J]. J Cell Sci, 2021, 134(20): jcs259134.
[71]	Wu H, Zheng RH, Hao ZD, et al. Cunninghamia lanceolata PSK peptide hormone genes promote primary root growth and adventitious root formation[J]. Plants(Basel), 2019, 8(11): 520.
[72]	Ochatt S, Conreux C, Mcolo RM, et al. Phytosulfokine-alpha, an enhancer of in vitro regeneration competence in recalcitrant legumes[J]. Plant Cell Tiss Organ Cult, 2018, 135(2): 189-201. doi: 10.1007/s11240-018-1455-0
[73]	Han J, Tan JF, Tu LL, et al. A peptide hormone gene, GhPSK promotes fiber elongation and contributes to longer and finer cotton fiber[J]. Plant Biotechnol J, 2014, 12(7): 861-871. doi: 10.1111/pbi.2014.12.issue-7 URL
[74]	Campbell L, Turner SR. A comprehensive analysis of RALF proteins in green plants suggests there are two distinct functional groups[J]. Front Plant Sci, 2017, 8: 37. doi: 10.3389/fpls.2017.00037 pmid: 28174582
[75]	Stegmann M, Monaghan J, Smakowska-Luzan E, et al. The receptor kinase FER is a RALF-regulated scaffold controlling plant immune signaling[J]. Science, 2017, 355(6322): 287-289. doi: 10.1126/science.aal2541 pmid: 28104890
[76]	Pearce G, Yamaguchi Y, Munske G, et al. Structure-activity studies of RALF, Rapid Alkalinization Factor, reveal an essential-YISY-motif[J]. Peptides, 2010, 31(11): 1973-1977. doi: 10.1016/j.peptides.2010.08.012 URL
[77]	Xiao Y, Stegmann M, Han ZF, et al. Mechanisms of RALF peptide perception by a heterotypic receptor complex[J]. Nature, 2019, 572(7768): 270-274. doi: 10.1038/s41586-019-1409-7
[78]	Li C, Yeh FL, Cheung AY, et al. Glycosylphosphatidylinositol-anchored proteins as chaperones and co-receptors for FERONIA receptor kinase signaling in Arabidopsis[J]. eLife, 2015, 4: e06587.
[79]	Haruta M, Sabat G, Stecker K, et al. A peptide hormone and its receptor protein kinase regulate plant cell expansion[J]. Science, 2014, 343(6169): 408-411. doi: 10.1126/science.1244454 pmid: 24458638
[80]	Bergonci T, Ribeiro B, Ceciliato PHO, et al. Arabidopsis thaliana RALF1 opposes brassinosteroid effects on root cell elongation and lateral root formation[J]. J Exp Bot, 2014, 65(8): 2219-2230. doi: 10.1093/jxb/eru099 pmid: 24620000
[81]	Ge ZX, Bergonci T, Zhao YL, et al. Arabidopsis pollen tube integrity and sperm release are regulated by RALF-mediated signaling[J]. Science, 2017, 358(6370): 1596-1600. doi: 10.1126/science.aao3642 URL
[82]	Okuda S, Fujita S, Moretti A, et al. Molecular mechanism for the recognition of sequence-divergent CIF peptides by the plant receptor kinases GSO1/SGN3 and GSO2[J]. Proc Natl Acad Sci USA, 2020, 117(5): 2693-2703. doi: 10.1073/pnas.1911553117 pmid: 31964818
[83]	Fujita S, De Bellis D, Edel KH, et al. SCHENGEN receptor module drives localized ROS production and lignification in plant roots[J]. EMBO J, 2020, 39(9): e103894.
[84]	Doll NM, Royek S, Fujita S, et al. A two-way molecular dialogue between embryo and endosperm is required for seed development[J]. Science, 2020, 367(6476): 431-435. doi: 10.1126/science.aaz4131 pmid: 31974252
[85]	Roberts I, Smith S, De Rybel B, et al. The CEP family in land plants: evolutionary analyses, expression studies, and role in Arabidopsis shoot development[J]. J Exp Bot, 2013, 64(17): 5371-5381. doi: 10.1093/jxb/ert331 pmid: 24179095
[86]	Higashiyama T. Peptide signaling in pollen-pistil interactions[J]. Plant Cell Physiol, 2010, 51(2): 177-189. doi: 10.1093/pcp/pcq008 pmid: 20081210
[87]	孙翔, 程丽军, 刘志文, 等. 小肽激素调控植物生殖发育的研究进展[J]. 自然杂志, 2021, 43(2): 105-111.
	Sun X, Cheng LJ, Liu ZW, et al. Peptides regulators in plant reproduction[J]. Chin J Nat, 2021, 43(2): 105-111. doi: 10.3969/j.issn.0253-9608.2021.02.004
[88]	Liu C, Shen LP, Xiao Y, et al. Pollen PCP-B peptides unlock a stigma peptide-receptor kinase gating mechanism for pollination[J]. Science, 2021, 372(6538): 171-175. doi: 10.1126/science.abc6107 pmid: 33833120
[89]	McGurl B, Pearce G, Orozco-Cardenas M, et al., Structure, expression, and antisense inhibition of the systemin precursor gene[J]. Science, 1992, 255(5051): 1570-1573. doi: 10.1126/science.1549783 pmid: 1549783
[90]	Buonanno M, Coppola M, Di Lelio I, et al. Prosystemin, a prohormone that modulates plant defense barriers, is an intrinsically disordered protein[J]. Protein Sci, 2018, 27(3): 620-632. doi: 10.1002/pro.3348 pmid: 29168260
[91]	de la Noval B, Pérez E, Martínez B, et al. Exogenous systemin has a contrasting effect on disease resistance in mycorrhizal tomato(Solanum lycopersicum)plants infected with necrotrophic or hemibiotrophic pathogens[J]. Mycorrhiza, 2007, 17(5): 449-460. doi: 10.1007/s00572-007-0122-9 URL
[92]	Wang L, Einig E, Almeida-Trapp M, et al. The systemin receptor SYR1 enhances resistance of tomato against herbivorous insects[J]. Nat Plants, 2018, 4(3): 152-156. doi: 10.1038/s41477-018-0106-0 pmid: 29459726
[93]	Cui YN, Li XJ, Yu M, et al. Sterols regulate endocytic pathways during flg22-induced defense responses in Arabidopsis[J]. Development, 2018, 145(19): dev165688.
[94]	Liu HW, Brettell LE. Plant defense by VOC-induced microbial priming[J]. Trends Plant Sci, 2019, 24(3): 187-189. doi: S1360-1385(19)30023-8 pmid: 30738790
[95]	Takahashi F, Suzuki T, Osakabe Y, et al. A small peptide modulates stomatal control via abscisic acid in long-distance signalling[J]. Nature, 2018, 556(7700): 235-238. doi: 10.1038/s41586-018-0009-2
[96]	Guo HQ, Nolan TM, Song GY, et al. FERONIA receptor kinase contributes to plant immunity by suppressing jasmonic acid signaling in Arabidopsis thaliana[J]. Curr Biol, 2018, 28(20): 3316-3324.e6. doi: 10.1016/j.cub.2018.07.078 URL
[97]	Chakravorty D, Yu YQ, Assmann SM. A kinase-dead version of FERONIA receptor-like kinase has dose-dependent impacts on rosette morphology and RALF1-mediated stomatal movements[J]. FEBS Lett, 2018, 592(20): 3429-3437. doi: 10.1002/1873-3468.13249 pmid: 30207378
[98]	Yu YQ, Assmann SM. Inter-relationships between the heterotrimeric Gβ subunit AGB1, the receptor-like kinase FERONIA, and RALF1 in salinity response[J]. Plant Cell Environ, 2018, 41(10): 2475-2489. doi: 10.1111/pce.v41.10 URL
[99]	Zhang H, Hu ZJ, Lei C, et al. A plant phytosulfokine peptide initiates auxin-dependent immunity through cytosolic Ca²⁺ signaling in tomato[J]. Plant Cell, 2018, 30(3): 652-667. doi: 10.1105/tpc.17.00537 URL
[100]	Igarashi D, Tsuda K, Katagiri F. The peptide growth factor, phytosulfokine, attenuates pattern-triggered immunity[J]. Plant J, 2012, 71(2): 194-204. doi: 10.1111/tpj.2012.71.issue-2 URL
[101]	Mosher S, Seybold H, Rodriguez P, et al. The tyrosine-sulfated peptide receptors PSKR1 and PSY1R modify the immunity of Arabidopsis to biotrophic and necrotrophic pathogens in an antagonistic manner[J]. Plant J, 2013, 73(3): 469-482. doi: 10.1111/tpj.12050 URL
[102]	Motose H, Iwamoto K, Endo S, et al. Involvement of phytosulfokine in the attenuation of stress response during the transdifferentiation of zinnia mesophyll cells into tracheary elements[J]. Plant Physiol, 2009, 150(1): 437-447. doi: 10.1104/pp.109.135954 pmid: 19270060
[103]	Li XM, Han HP, Chen M, et al. Overexpression of OsDT11, which encodes a novel cysteine-rich peptide, enhances drought tolerance and increases ABA concentration in rice[J]. Plant Mol Biol, 2017, 93(1): 21-34. doi: 10.1007/s11103-016-0544-x URL
[104]	Nakaminami K, Okamoto M, Higuchi-Takeuchi M, et al. AtPep3 is a hormone-like peptide that plays a role in the salinity stress tolerance of plants[J]. Proc Natl Acad Sci USA, 2018, 115(22): 5810-5815. doi: 10.1073/pnas.1719491115 pmid: 29760074
[105]	Chien PS, Nam HG, Chen YR. A salt-regulated peptide derived from the CAP superfamily protein negatively regulates salt-stress tolerance in Arabidopsis[J]. J Exp Bot, 2015, 66(17): 5301-5313. doi: 10.1093/jxb/erv263 URL
[106]	Xu C, Liberatore KL, MacAlister CA, et al. A cascade of Arabinosyltransferases controls shoot meristem size in tomato[J]. Nat Genet, 2015, 47(7): 784-792. doi: 10.1038/ng.3309 pmid: 26005869

家族 Family	名称 Name	受体 Receptor	加工过程 Processing	功能 Fuction	参考文献References
SYS	SYS	SYR1	非富含Cys 非翻译	介导植物防御的反应	[32-33]
CLE	CLV3	CLV1, CLV2, SOL2/CRN	Pro羟基化羟脯氨酸阿拉伯糖基化	维持茎尖干细胞的正常分化	[24,34 -35]
	CLE25/26/45	BAM1/3		维持茎尖和根尖分生组织的稳态	[36-37]
	TDIF	TDR/PXY		促进原形成层细胞增殖，抑制其分化成木质部筛管	[38]
	CLE45	BAM3		抑制RAM中的初生韧皮部筛分子的分化	[35]
	CLE9/10	BAM1, HSL1		抑制木质部位置上的木质部前体细胞的平周分裂；依赖ABA信号通路调控气孔的关闭	[39]
CIF	CIF1, CIF2	GSO1/SGN3	Pro羟基化 Tyr硫酸化	调控凯氏带的完整性	[40]
CIF	CIF3, CIF4	GSO1/SGN3, GSO2	Pro羟基化 Tyr硫酸化	调控绒毡层发育和花粉壁形成	[41]
PSK	PSK-α	PSKR1, PSKR2	Tyr硫酸化	调节根和下胚轴细胞的伸长、花粉管的生长、体细胞胚胎发生、体外再生能力和豆科结瘤过程；调节生物营养和坏死病原体的免疫反应	[42⇓⇓-45]
	PSK-γ			促进营养器官和种子的生长	[46]
	PSK-δ			增加豆科植物的根瘤菌数量，促进共生结瘤	[47]
RALFs	RALF1	FER, BAK1	富含Cys 形成二硫键	抑制植物侧根的发育；抑制根生长和细胞伸长	[48⇓-50]
	RALF34	THE1, ANX1/2-BUPS1/2		调控侧根发育；使花粉管破裂释放精子完成双受精	[51-52]
	RALF4/19	ANX1/2-BUPS1/2		调控花粉管的生长和完整性	[53]

家族 Family	名称 Name	受体 Receptor	加工过程 Processing	功能 Fuction	参考文献References
SYS	SYS	SYR1	非富含Cys 非翻译	介导植物防御的反应	[32-33]
CLE	CLV3	CLV1, CLV2, SOL2/CRN	Pro羟基化羟脯氨酸阿拉伯糖基化	维持茎尖干细胞的正常分化	[24,34 -35]
	CLE25/26/45	BAM1/3		维持茎尖和根尖分生组织的稳态	[36-37]
	TDIF	TDR/PXY		促进原形成层细胞增殖，抑制其分化成木质部筛管	[38]
	CLE45	BAM3		抑制RAM中的初生韧皮部筛分子的分化	[35]
	CLE9/10	BAM1, HSL1		抑制木质部位置上的木质部前体细胞的平周分裂；依赖ABA信号通路调控气孔的关闭	[39]
CIF	CIF1, CIF2	GSO1/SGN3	Pro羟基化 Tyr硫酸化	调控凯氏带的完整性	[40]
CIF	CIF3, CIF4	GSO1/SGN3, GSO2	Pro羟基化 Tyr硫酸化	调控绒毡层发育和花粉壁形成	[41]
PSK	PSK-α	PSKR1, PSKR2	Tyr硫酸化	调节根和下胚轴细胞的伸长、花粉管的生长、体细胞胚胎发生、体外再生能力和豆科结瘤过程；调节生物营养和坏死病原体的免疫反应	[42⇓⇓-45]
	PSK-γ			促进营养器官和种子的生长	[46]
	PSK-δ			增加豆科植物的根瘤菌数量，促进共生结瘤	[47]
RALFs	RALF1	FER, BAK1	富含Cys 形成二硫键	抑制植物侧根的发育；抑制根生长和细胞伸长	[48⇓-50]
	RALF34	THE1, ANX1/2-BUPS1/2		调控侧根发育；使花粉管破裂释放精子完成双受精	[51-52]
	RALF4/19	ANX1/2-BUPS1/2		调控花粉管的生长和完整性	[53]

小肽激素调控植物生长发育及逆境生理研究进展

Advances in the Regulation of Plant Growth, Development and Stress Physiology by Small Peptide Hormones

RichHTML

PDF (PC)

可视化

摘要/Abstract

引用本文

使用本文

图/表 3

参考文献 106

相关文章 15

编辑推荐

Metrics

本文评价

[1]	李托, 李陇平, 屈雷. 有尾噬菌体的结构及其受体研究进展[J]. 生物技术通报, 2023, 39(6): 88-101.
[2]	冯珊珊, 王璐, 周益, 王幼平, 方玉洁. WOX家族基因调控植物生长发育和非生物胁迫响应的研究进展[J]. 生物技术通报, 2023, 39(5): 1-13.
[3]	薛皦, 朱庆锋, 冯彦钊, 陈沛, 刘文华, 张爱霞, 刘勤坚, 张琪, 于洋. 植物基因上游开放阅读框的研究进展[J]. 生物技术通报, 2023, 39(4): 157-165.
[4]	魏明, 王欣玉, 伍国强, 赵萌. NAD依赖型去乙酰化酶SRT在植物表观遗传调控中的作用[J]. 生物技术通报, 2023, 39(4): 59-70.
[5]	桑田, 王鹏程. 植物SUMO化修饰研究进展[J]. 生物技术通报, 2023, 39(3): 1-12.
[6]	陈广霞, 李秀杰, 蒋锡龙, 单雷, 张志昌, 李勃. 植物小分子信号肽参与非生物逆境胁迫应答的研究进展[J]. 生物技术通报, 2023, 39(11): 61-73.
[7]	孙雨桐, 刘德帅, 齐迅, 冯美, 黄栩筝, 姚文孔. 茉莉酸调控植物生长发育和胁迫的研究进展[J]. 生物技术通报, 2023, 39(11): 99-109.
[8]	安昌, 陆琳, 沈梦千, 陈盛圳, 叶康卓, 秦源, 郑平. 植物bHLH基因家族研究进展及在药用植物中的应用前景[J]. 生物技术通报, 2023, 39(10): 1-16.
[9]	陈英, 王艺磊, 邹鹏飞. 大黄鱼TRAF6的克隆及表达分析[J]. 生物技术通报, 2022, 38(8): 233-243.
[10]	汤茜茜, 林楚宇, 陶增. 植物组蛋白去甲基化酶研究进展[J]. 生物技术通报, 2022, 38(7): 13-22.
[11]	李萍, 郭发平, 田敏, 税阳, 徐娜娜, 白大嵩, 余德金, 张杰, 胡运高, 彭友林. 甾醇在调节植物生长发育中的研究进展[J]. 生物技术通报, 2022, 38(7): 90-98.
[12]	古盼, 齐学影, 李莉, 张曦, 单晓昳. AtRGS1胞吞动态调控G蛋白参与拟南芥生长发育和抗性反应[J]. 生物技术通报, 2022, 38(6): 34-42.
[13]	李洋, 张晓天, 朴静子, 周如军, 李自博, 关海雯. 花生疮痂病菌蓝光受体EaWC 1基因克隆及生物信息学分析[J]. 生物技术通报, 2022, 38(5): 93-99.
[14]	悦曼芳, 张春, 吴忠义. 植物转录因子AP2/ERF家族蛋白结构和功能的研究进展[J]. 生物技术通报, 2022, 38(12): 11-26.
[15]	汤晓丽, 姜福东, 张洪霞. 植物SINA E3泛素连接酶功能的研究进展[J]. 生物技术通报, 2022, 38(10): 10-17.