植物SINA E3泛素连接酶功能的研究进展

doi:10.13560/j.cnki.biotech.bull.1985.2021-1301

摘要/Abstract

摘要：

泛素-蛋白酶体系统（ubiquitin-proteasome system，UPS）是生物体中一种重要的蛋白平衡调节系统，通过泛素化降解不同的靶蛋白，参与细胞中复杂多样的生命活动过程。SINA E3泛素连接酶是UPS系统中E3泛素连接酶的一个重要类型，具有广泛而重要的生物学作用。本研究阐述了植物SINA E3泛素连接酶的功能研究现状。围绕SINA E3泛素连接酶在植物正常生长发育、逆境胁迫响应、植物与其他生物的相互作用以及植物细胞自噬4个方面展开论述。总结了目前植物SINA E3泛素连接酶的生物学功能，同时也指出了植物SINA E3泛素连接酶功能研究所面临的诸多问题及对未来的展望，为植物SINA E3泛素连接酶功能的进一步研究提供参考。

关键词: SINA E3泛素连接酶, 生长发育, 逆境胁迫, 生物互作, 细胞自噬

Abstract:

The ubiquitin-proteasome system（UPS）is an important regulatory system for proteostasis in organisms. By means of degrading different target proteins，UPS participates in diverse cellular processes. SINA E3 ubiquitin ligase is a key type of E3 ubiquitin ligases of UPS，playing extensive and important biological functions. This research elaborated the functional research status of SINA E3 ubiquitin ligase since the first one was discovered in plant. Four main aspects of its functions，including in plant growth and development，plant responses under adverse environment，interactions between plant and other organisms and plant autophagy were expounded. Generally，all the reported functions of SINA E3 ubiquitin ligase in plant were summarized. Meanwhile，the existing issues and research prospects for functional study of SINA E3 in plant are proposed. Therefore，all the above would provide valuable reference for the further functional research of SINA E3 in the future.

Key words: SINA E3 ubiquitin ligase, growth and development, abiotic stress, interactions between organisms, autophagy

汤晓丽, 姜福东, 张洪霞. 植物SINA E3泛素连接酶功能的研究进展[J]. 生物技术通报, 2022, 38(10): 10-17.

TANG Xiao-li, JIANG Fu-dong, ZHANG Hong-xia. Research Progress in the Functions of SINA E3 Ubiquitin Ligase in Plant[J]. Biotechnology Bulletin, 2022, 38(10): 10-17.

图/表 1

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物种Species	基因名称Gene name	登录号Accession No.	基因座/位置Locus/Location	参考文献Reference
拟南芥Arabidopsis thaliana	AtSINA1	NP_181729.1	At2g41980	[17]
	AtSINA2	NP_191363.1	At3g58040
	AtSINA3	NP_567118.1	At3g61790
	AtSINA4	NP_194517.1	At4g27880
	AtSINA5	AAM11573.1	At5g53360
杨树Populus trichocarpa	PtSINA1	fgenesh4_pg.C_LG_I000093	LG_I：670238-671581	[17]
	PtSINA2	fgenesh4_pm.C_LG_I000095	LG_I：2115588-2117000
	PtSINA3	gw1.II.2951.1	LG_II：13177725-13180474
	PtSINA4	estExt_Genewise1_v1.C_LG_III0871	LG_III：17277104-17281238
	PtSINA5	eugene3.00031885	LG_III：18885651-18887185
	PtSINA6	estExt_Genewise1_v1.C_LG_VI0616	LG_VI：10945383-10948295
	PtSINA7	estExt_fgenesh4_pg.C_LG_XII0205	LG_XII：1967106-1970129
	PtSINA8	gw1.XIV.1720.1	LG_XIV：3531188-3533571
	PtSINA9	gw1.XV.382.1	LG_XV：877405-880050
	PtSINA10	grail3.0004018901	LG_XVI：3971458-3975863
水稻Oryza sativa	OsSINA1	NP_001042518.1	Os01g13370	[17]
	OsSINA2	NP_001045773.1	Os02g03620
	OsSINA3	NP_001046599.1	Os02g19140
	OsSINA4	ABF96019	Os03g24040
	OsSINA5	NP_001054994.1	Os05g14860
	OsSINA6	NP_001060528.1	Os07g46560
玉米Zea mays	ZmSINA1	EF434384	100170242	[17]
	ZmSINA2	EF434387	100170245
	ZmSINA3	EF434383	103626898
	ZmSINA4	EF434385	100170243
	ZmSINA5	EF434382	100170241
	ZmSINA6	EF434386	100170244
苜蓿Medicago truncatula	MtSINA1	ABW70159.1	EU189945	[18]
	MtSINA2	ABW70160.1	EU189946
	MtSINA3	ABW70161.1	EU189947
	MtSINA4	ABW70162.1	EU189948
	MtSINA5	ABW70163.1	EU189949
	MtSINA6	ABW70164.1	EU189950
百脉根Lotus japonicus	LjSINA1	CCG06551.1	HE664113	[19]
	LjSINA2	CCG06552.1	HE664114
	LjSINA3	CCG06553.1	HE664115
	LjSINA4	CCG06554.1	HE664116
	LjSINA5	CCG06555.1	HE664117
	LjSINA6	CCG06556.1	HE664118
番茄Solanum lycopersicum	SlSINA1	AK324518	101263446	[20]
	SlSINA2	BT013026	101253831
	SlSINA3	AK322153	101246723
	SlSINA4	AK320390	101258961
	SlSINA5	AK321160	101263446
	SlSINA6	XM_004248034	101264159
苹果Malus×domestica	MdSINA1	MD01G1082000	Chr.01：18851198-18855278	[21]
	MdSINA2	MD01G1218700	Chr.01：31083173-31086177
	MdSINA3	MD02G1290000	Chr.02：34598424-34602594
	MdSINA4	MD03G1012000	Chr.03：919096-923194
	MdSINA5	MD06G1109400	Chr.06：24892232-24897122
	MdSINA6	MD07G1037000	Chr.07：3041621-3045379
	MdSINA7	MD07G1150400	Chr.07：21874143-21877048
	MdSINA8	MD07G1288600	Chr.07：34966306-34969128
	MdSINA9	MD11G1014900	Chr.11：1183310-1187186
	MdSINA10	MD12G1055100	Chr12：6229125-6233025
	MdSINA11	MD14G1054300	Chr.14：5470040-5474302
香蕉Musa acuminata	MaSINA1	XP_009416451	103997048	[22]

物种Species	基因名称Gene name	登录号Accession No.	基因座/位置Locus/Location	参考文献Reference
拟南芥Arabidopsis thaliana	AtSINA1	NP_181729.1	At2g41980	[17]
	AtSINA2	NP_191363.1	At3g58040
	AtSINA3	NP_567118.1	At3g61790
	AtSINA4	NP_194517.1	At4g27880
	AtSINA5	AAM11573.1	At5g53360
杨树Populus trichocarpa	PtSINA1	fgenesh4_pg.C_LG_I000093	LG_I：670238-671581	[17]
	PtSINA2	fgenesh4_pm.C_LG_I000095	LG_I：2115588-2117000
	PtSINA3	gw1.II.2951.1	LG_II：13177725-13180474
	PtSINA4	estExt_Genewise1_v1.C_LG_III0871	LG_III：17277104-17281238
	PtSINA5	eugene3.00031885	LG_III：18885651-18887185
	PtSINA6	estExt_Genewise1_v1.C_LG_VI0616	LG_VI：10945383-10948295
	PtSINA7	estExt_fgenesh4_pg.C_LG_XII0205	LG_XII：1967106-1970129
	PtSINA8	gw1.XIV.1720.1	LG_XIV：3531188-3533571
	PtSINA9	gw1.XV.382.1	LG_XV：877405-880050
	PtSINA10	grail3.0004018901	LG_XVI：3971458-3975863
水稻Oryza sativa	OsSINA1	NP_001042518.1	Os01g13370	[17]
	OsSINA2	NP_001045773.1	Os02g03620
	OsSINA3	NP_001046599.1	Os02g19140
	OsSINA4	ABF96019	Os03g24040
	OsSINA5	NP_001054994.1	Os05g14860
	OsSINA6	NP_001060528.1	Os07g46560
玉米Zea mays	ZmSINA1	EF434384	100170242	[17]
	ZmSINA2	EF434387	100170245
	ZmSINA3	EF434383	103626898
	ZmSINA4	EF434385	100170243
	ZmSINA5	EF434382	100170241
	ZmSINA6	EF434386	100170244
苜蓿Medicago truncatula	MtSINA1	ABW70159.1	EU189945	[18]
	MtSINA2	ABW70160.1	EU189946
	MtSINA3	ABW70161.1	EU189947
	MtSINA4	ABW70162.1	EU189948
	MtSINA5	ABW70163.1	EU189949
	MtSINA6	ABW70164.1	EU189950
百脉根Lotus japonicus	LjSINA1	CCG06551.1	HE664113	[19]
	LjSINA2	CCG06552.1	HE664114
	LjSINA3	CCG06553.1	HE664115
	LjSINA4	CCG06554.1	HE664116
	LjSINA5	CCG06555.1	HE664117
	LjSINA6	CCG06556.1	HE664118
番茄Solanum lycopersicum	SlSINA1	AK324518	101263446	[20]
	SlSINA2	BT013026	101253831
	SlSINA3	AK322153	101246723
	SlSINA4	AK320390	101258961
	SlSINA5	AK321160	101263446
	SlSINA6	XM_004248034	101264159
苹果Malus×domestica	MdSINA1	MD01G1082000	Chr.01：18851198-18855278	[21]
	MdSINA2	MD01G1218700	Chr.01：31083173-31086177
	MdSINA3	MD02G1290000	Chr.02：34598424-34602594
	MdSINA4	MD03G1012000	Chr.03：919096-923194
	MdSINA5	MD06G1109400	Chr.06：24892232-24897122
	MdSINA6	MD07G1037000	Chr.07：3041621-3045379
	MdSINA7	MD07G1150400	Chr.07：21874143-21877048
	MdSINA8	MD07G1288600	Chr.07：34966306-34969128
	MdSINA9	MD11G1014900	Chr.11：1183310-1187186
	MdSINA10	MD12G1055100	Chr12：6229125-6233025
	MdSINA11	MD14G1054300	Chr.14：5470040-5474302
香蕉Musa acuminata	MaSINA1	XP_009416451	103997048	[22]