生物技术通报 ›› 2013, Vol. 0 ›› Issue (10): 1-5.

• 综述与专论 •    下一篇

拟南芥和水稻JMJC蛋白的研究进展

秦巧,张海文,黄荣峰   

  1. (中国农业科学院生物技术研究所,北京 100081)
  • 收稿日期:2013-04-23 出版日期:2013-10-14 发布日期:2013-10-15
  • 作者简介:秦巧, 硕士研究生, 研究方向: 植物抗逆分子生物学;E-mail :tsinemail@163.com
  • 基金资助:
    国家自然科学基金项目(31271638)

Advance on JMJC Proteins in Arabidopsis and Oryza sativa

Qin Qiao, Zhang Haiwen, Huang Rongfeng   

  1. (Biotechnology Research Institute,Chinese Academy of Agricultural Sciences,Beijing 100081)
  • Received:2013-04-23 Published:2013-10-14 Online:2013-10-15

摘要: 表观遗传学是研究在基因的DNA 序列没有改变的情况下,但功能发生了可遗传性变化的遗传学分支学科。JMJC 蛋白是表观遗传学调控中的一类关键酶,其功能是催化组蛋白赖氨酸的去甲基化,通过染色质重塑或基因组印迹等途径调控基因的表达,影响植物的生长发育。综述拟南芥和水稻JMJC 蛋白家族的近期研究进展,以期探讨JMJC 组蛋白去甲基化酶对拟南芥和水稻生长发育的影响及其调控的分子基础。

关键词: 表观遗传学, 组蛋白, 去甲基化, 水稻, 拟南芥, JMJC 蛋白

Abstract: Epigenetics is to study heritable changes in gene expression and function that occur without a change in DNA sequence.
Jumonji C(jmjC)domain-containing proteins have been identified as histone lysine demethylases, which regulate gene expression and plant development though influencing chromatin remodeling, genomic imprinting or other approaches. In this review, we described the research advance of JMJC proteins during recent years, which could provide a reference for further exploring how JMJC histone demethylases influence the growth and development processes in Arabidopsis and rice.

Key words: Epigenetics, Histone demethylation, Rice, Arabidopsis, JMJC proteins