Research Progress on Induced Pluripotent Stem Cells in Hematopoietic Diseases

doi:10.13560/j.cnki.biotech.bull.1985.2016.04.004

Abstract

Abstract: Hematopoietic stem cell transplantation for the treatment of blood system diseases has been had great progress. However，due to the issues of limited donor and matching efficiency is not high，which seriously hindered its wide application in clinic. It is imperative to seek more secure，economical and effective resources of hematopoietic stem cell. Induced pluripotent stem cells can be differentiated into a variety of cells in vitro，especially deeper research on induced differentiation into hematopoietic stem cells in vitro. In this paper，iPS cells directed differentiation to hematopoietic stem cells in vitro and research progress on transplant are reviewed.

Key words: hematopoietic stem cell transplantation, induced pluripotent stem cells, hematopoietic differentiation

FAN Di ,SUN Xiao-fang. Research Progress on Induced Pluripotent Stem Cells in Hematopoietic Diseases[J]. Biotechnology Bulletin, 2016, 32(4): 34-38.

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